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Unique error signature of the four-subunit yeast DNA polymerase epsilon.
Shcherbakova PV, Pavlov YI, Chilkova O, Rogozin IB, Johansson E, Kunkel TA. Shcherbakova PV, et al. J Biol Chem. 2003 Oct 31;278(44):43770-80. doi: 10.1074/jbc.M306893200. Epub 2003 Jul 25. J Biol Chem. 2003. PMID: 12882968
Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase ε.
Parkash V, Kulkarni Y, Ter Beek J, Shcherbakova PV, Kamerlin SCL, Johansson E. Parkash V, et al. Among authors: shcherbakova pv. Nat Commun. 2019 Jan 22;10(1):373. doi: 10.1038/s41467-018-08114-9. Nat Commun. 2019. PMID: 30670696 Free PMC article.
Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae.
Barbari SR, Kane DP, Moore EA, Shcherbakova PV. Barbari SR, et al. Among authors: shcherbakova pv. G3 (Bethesda). 2018 Mar 2;8(3):1019-1029. doi: 10.1534/g3.118.200042. G3 (Bethesda). 2018. PMID: 29352080 Free PMC article.
A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotype, indicating fidelity defects distinct from loss of proofreading.
Kane DP, Shcherbakova PV. Kane DP, et al. Among authors: shcherbakova pv. Cancer Res. 2014 Apr 1;74(7):1895-901. doi: 10.1158/0008-5472.CAN-13-2892. Epub 2014 Feb 13. Cancer Res. 2014. PMID: 24525744 Free PMC article.
The non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell nuclear antigen (PCNA) regulates the Rev1-PCNA interaction and Polζ/Rev1-dependent translesion DNA synthesis.
Sharma NM, Kochenova OV, Shcherbakova PV. Sharma NM, et al. Among authors: shcherbakova pv. J Biol Chem. 2011 Sep 23;286(38):33557-66. doi: 10.1074/jbc.M110.206680. Epub 2011 Jul 28. J Biol Chem. 2011. PMID: 21799021 Free PMC article.
A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability.
Daee DL, Mertz TM, Shcherbakova PV. Daee DL, et al. Among authors: shcherbakova pv. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):157-62. doi: 10.1073/pnas.0907526106. Epub 2009 Dec 4. Proc Natl Acad Sci U S A. 2010. PMID: 19966286 Free PMC article.
A novel function of DNA polymerase zeta regulated by PCNA.
Northam MR, Garg P, Baitin DM, Burgers PM, Shcherbakova PV. Northam MR, et al. Among authors: shcherbakova pv. EMBO J. 2006 Sep 20;25(18):4316-25. doi: 10.1038/sj.emboj.7601320. Epub 2006 Sep 7. EMBO J. 2006. PMID: 16957771 Free PMC article.
DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair.
Hall MC, Shcherbakova PV, Fortune JM, Borchers CH, Dial JM, Tomer KB, Kunkel TA. Hall MC, et al. Among authors: shcherbakova pv. Nucleic Acids Res. 2003 Apr 15;31(8):2025-34. doi: 10.1093/nar/gkg324. Nucleic Acids Res. 2003. PMID: 12682353 Free PMC article.
Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins.
Hall MC, Shcherbakova PV, Kunkel TA. Hall MC, et al. Among authors: shcherbakova pv. J Biol Chem. 2002 Feb 1;277(5):3673-9. doi: 10.1074/jbc.M106120200. Epub 2001 Nov 20. J Biol Chem. 2002. PMID: 11717305
DNA binding properties of the yeast Msh2-Msh6 and Mlh1-Pms1 heterodimers.
Drotschmann K, Hall MC, Shcherbakova PV, Wang H, Erie DA, Brownewell FR, Kool ET, Kunkel TA. Drotschmann K, et al. Among authors: shcherbakova pv. Biol Chem. 2002 Jun;383(6):969-75. doi: 10.1515/BC.2002.103. Biol Chem. 2002. PMID: 12222686 Review.
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