Shea BS - Search Results

1

The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.

Tager AM, LaCamera P, Shea BS, Campanella GS, Selman M, Zhao Z, Polosukhin V, Wain J, Karimi-Shah BA, Kim ND, Hart WK, Pardo A, Blackwell TS, Xu Y, Chun J, Luster AD. Tager AM, et al. Among authors: shea bs. Nat Med. 2008 Jan;14(1):45-54. doi: 10.1038/nm1685. Epub 2007 Dec 9. Nat Med. 2008. PMID: 18066075

2

Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury.

Shea BS, Brooks SF, Fontaine BA, Chun J, Luster AD, Tager AM. Shea BS, et al. Am J Respir Cell Mol Biol. 2010 Dec;43(6):662-73. doi: 10.1165/rcmb.2009-0345OC. Epub 2010 Jan 15. Am J Respir Cell Mol Biol. 2010. PMID: 20081052 Free PMC article.

3

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression.

Liu F, Mih JD, Shea BS, Kho AT, Sharif AS, Tager AM, Tschumperlin DJ. Liu F, et al. Among authors: shea bs. J Cell Biol. 2010 Aug 23;190(4):693-706. doi: 10.1083/jcb.201004082. J Cell Biol. 2010. PMID: 20733059 Free PMC article.

4

Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation.

Lagares D, Busnadiego O, García-Fernández RA, Kapoor M, Liu S, Carter DE, Abraham D, Shi-Wen X, Carreira P, Fontaine BA, Shea BS, Tager AM, Leask A, Lamas S, Rodríguez-Pascual F. Lagares D, et al. Among authors: shea bs. Arthritis Rheum. 2012 May;64(5):1653-64. doi: 10.1002/art.33482. Arthritis Rheum. 2012. PMID: 22492165 Free PMC article.

5

Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.

Shea BS, Tager AM. Shea BS, et al. Proc Am Thorac Soc. 2012 Jul;9(3):102-10. doi: 10.1513/pats.201201-005AW. Proc Am Thorac Soc. 2012. PMID: 22802282 Free PMC article. Review.

6

Sphingolipid regulation of tissue fibrosis.

Shea BS, Tager AM. Shea BS, et al. Open Rheumatol J. 2012;6:123-9. doi: 10.2174/1874312901206010123. Epub 2012 Jun 15. Open Rheumatol J. 2012. PMID: 22802910 Free PMC article.

7

Docosatetraenoyl LPA is elevated in exhaled breath condensate in idiopathic pulmonary fibrosis.

Montesi SB, Mathai SK, Brenner LN, Gorshkova IA, Berdyshev EV, Tager AM, Shea BS. Montesi SB, et al. Among authors: shea bs. BMC Pulm Med. 2014 Jan 27;14:5. doi: 10.1186/1471-2466-14-5. BMC Pulm Med. 2014. PMID: 24468008 Free PMC article.

8

New therapeutic targets in idiopathic pulmonary fibrosis. Aiming to rein in runaway wound-healing responses.

Ahluwalia N, Shea BS, Tager AM. Ahluwalia N, et al. Among authors: shea bs. Am J Respir Crit Care Med. 2014 Oct 15;190(8):867-78. doi: 10.1164/rccm.201403-0509PP. Am J Respir Crit Care Med. 2014. PMID: 25090037 Free PMC article. Review.

9

Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis.

Black KE, Berdyshev E, Bain G, Castelino FV, Shea BS, Probst CK, Fontaine BA, Bronova I, Goulet L, Lagares D, Ahluwalia N, Knipe RS, Natarajan V, Tager AM. Black KE, et al. Among authors: shea bs. FASEB J. 2016 Jun;30(6):2435-50. doi: 10.1096/fj.201500197R. Epub 2016 Mar 22. FASEB J. 2016. PMID: 27006447 Free PMC article.

10

Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis.

Shea BS, Probst CK, Brazee PL, Rotile NJ, Blasi F, Weinreb PH, Black KE, Sosnovik DE, Van Cott EM, Violette SM, Caravan P, Tager AM. Shea BS, et al. JCI Insight. 2017 May 4;2(9):e86608. doi: 10.1172/jci.insight.86608. eCollection 2017 May 4. JCI Insight. 2017. PMID: 28469072 Free PMC article.

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