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Multivalent lipid targeting by the calcium-independent C2A domain of synaptotagmin-like protein 4/granuphilin.
Alnaas AA, Watson-Siriboe A, Tran S, Negussie M, Henderson JA, Osterberg JR, Chon NL, Harrott BM, Oviedo J, Lyakhova T, Michel C, Reisdorph N, Reisdorph R, Shearn CT, Lin H, Knight JD. Alnaas AA, et al. Among authors: shearn ct. J Biol Chem. 2021 Jan-Jun;296:100159. doi: 10.1074/jbc.RA120.014618. Epub 2020 Dec 10. J Biol Chem. 2021. PMID: 33277360 Free PMC article.
Cholestatic liver disease results increased production of reactive aldehydes and an atypical periportal hepatic antioxidant response.
Shearn CT, Fennimore B, Orlicky DJ, Gao YR, Saba LM, Battista KD, Aivazidis S, Assiri M, Harris PS, Michel C, Merrill GF, Schmidt EE, Colgan SP, Petersen DR. Shearn CT, et al. Free Radic Biol Med. 2019 Nov 1;143:101-114. doi: 10.1016/j.freeradbiomed.2019.07.036. Epub 2019 Aug 1. Free Radic Biol Med. 2019. PMID: 31377417 Free PMC article.
4-Hydroxynonenal inhibits SIRT3 via thiol-specific modification.
Fritz KS, Galligan JJ, Smathers RL, Roede JR, Shearn CT, Reigan P, Petersen DR. Fritz KS, et al. Among authors: shearn ct. Chem Res Toxicol. 2011 May 16;24(5):651-62. doi: 10.1021/tx100355a. Epub 2011 Apr 14. Chem Res Toxicol. 2011. PMID: 21449565 Free PMC article.
54 results