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Oxygen gradient ektacytometry-derived biomarkers are associated with vaso-occlusive crises and correlate with treatment response in sickle cell disease.
Rab MAE, Kanne CK, Bos J, van Oirschot BA, Boisson C, Houwing ME, Gerritsma J, Teske E, Renoux C, Riedl J, Schutgens REG, Bartels M, Nur E, Joly P, Fort R, Cnossen MH, van Wijk R, Connes P, van Beers EJ, Sheehan VA. Rab MAE, et al. Among authors: sheehan va. Am J Hematol. 2020 Oct 23. doi: 10.1002/ajh.26031. Online ahead of print. Am J Hematol. 2020. PMID: 33095451 No abstract available.
A novel algorithm comprehensively characterizes human RH genes using whole-genome sequencing data.
Chang TC, Haupfear KM, Yu J, Rampersaud E, Sheehan VA, Flanagan JM, Hankins JS, Weiss MJ, Wu G, Vege S, Westhoff CM, Chou ST, Zheng Y. Chang TC, et al. Among authors: sheehan va. Blood Adv. 2020 Sep 22;4(18):4347-4357. doi: 10.1182/bloodadvances.2020002148. Blood Adv. 2020. PMID: 32915977 Free PMC article.
The vaso-occlusive pain crisis in sickle cell disease: Definition, pathophysiology, and management.
Darbari DS, Sheehan VA, Ballas SK. Darbari DS, et al. Among authors: sheehan va. Eur J Haematol. 2020 Sep;105(3):237-246. doi: 10.1111/ejh.13430. Epub 2020 May 19. Eur J Haematol. 2020. PMID: 32301178 Review.
Blood rheology biomarkers in sickle cell disease.
Lu M, Rab MA, Shevkoplyas SS, Sheehan VA. Lu M, et al. Among authors: sheehan va. Exp Biol Med (Maywood). 2020 Jan;245(2):155-165. doi: 10.1177/1535370219900494. Epub 2020 Jan 16. Exp Biol Med (Maywood). 2020. PMID: 31948290 Review.
End points for sickle cell disease clinical trials: patient-reported outcomes, pain, and the brain.
Farrell AT, Panepinto J, Carroll CP, Darbari DS, Desai AA, King AA, Adams RJ, Barber TD, Brandow AM, DeBaun MR, Donahue MJ, Gupta K, Hankins JS, Kameka M, Kirkham FJ, Luksenburg H, Miller S, Oneal PA, Rees DC, Setse R, Sheehan VA, Strouse J, Stucky CL, Werner EM, Wood JC, Zempsky WT. Farrell AT, et al. Among authors: sheehan va. Blood Adv. 2019 Dec 10;3(23):3982-4001. doi: 10.1182/bloodadvances.2019000882. Blood Adv. 2019. PMID: 31809538 Free PMC article.
Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry.
Rab MAE, van Oirschot BA, Bos J, Kanne CK, Sheehan VA, van Beers EJ, van Wijk R. Rab MAE, et al. Among authors: sheehan va. J Vis Exp. 2019 Nov 5;(153). doi: 10.3791/60213. J Vis Exp. 2019. PMID: 31762454
Methodological aspects of the oxygenscan in sickle cell disease: A need for standardization.
Rab MAE, Kanne CK, Bos J, Boisson C, van Oirschot BA, Nader E, Renoux C, Joly P, Fort R, van Beers EJ, Sheehan VA, van Wijk R, Connes P. Rab MAE, et al. Among authors: sheehan va. Am J Hematol. 2020 Jan;95(1):E5-E8. doi: 10.1002/ajh.25655. Epub 2019 Oct 26. Am J Hematol. 2020. PMID: 31591742 Free PMC article. No abstract available.
A novel high-throughput molecular counting method with single base-pair resolution enables accurate single-gene NIPT.
Tsao DS, Silas S, Landry BP, Itzep NP, Nguyen AB, Greenberg S, Kanne CK, Sheehan VA, Sharma R, Shukla R, Arora PN, Atay O. Tsao DS, et al. Among authors: sheehan va. Sci Rep. 2019 Oct 7;9(1):14382. doi: 10.1038/s41598-019-50378-8. Sci Rep. 2019. PMID: 31591409 Free PMC article.
Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease.
Park SH, Lee CM, Dever DP, Davis TH, Camarena J, Srifa W, Zhang Y, Paikari A, Chang AK, Porteus MH, Sheehan VA, Bao G. Park SH, et al. Among authors: sheehan va. Nucleic Acids Res. 2019 Sep 5;47(15):7955-7972. doi: 10.1093/nar/gkz475. Nucleic Acids Res. 2019. PMID: 31147717 Free PMC article.
Spontaneous healing of avascular necrosis of the femoral head in sickle cell disease.
Itzep NP, Jadhav SP, Kanne CK, Sheehan VA. Itzep NP, et al. Among authors: sheehan va. Am J Hematol. 2019 Jun;94(6):E160-E162. doi: 10.1002/ajh.25453. Epub 2019 Mar 18. Am J Hematol. 2019. PMID: 30838665 Free article. No abstract available.
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