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Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein.
Gill SR, Schroer TA, Szilak I, Steuer ER, Sheetz MP, Cleveland DW. Gill SR, et al. J Cell Biol. 1991 Dec;115(6):1639-50. doi: 10.1083/jcb.115.6.1639. J Cell Biol. 1991. PMID: 1836789 Free PMC article.
Sheetz. 1991a. J. Cell Biol. 115:1309-1318.) stimulates dynein-mediated vesicle transport. A major component of the activator complex is a doublet of 150-kD polypeptides for which we propose the name dynactin (for dynein activator). ...
Sheetz. 1991a. J. Cell Biol. 115:1309-1318.) stimulates dynein-mediated vesicle transport. A major component of the activator complex
Cell migration by graded attachment to substrates and contraction.
Sheetz MP. Sheetz MP. Semin Cell Biol. 1994 Jun;5(3):149-55. doi: 10.1006/scel.1994.1019. Semin Cell Biol. 1994. PMID: 7919228 Review.
Force effects on biochemical kinetics.
Khan S, Sheetz MP. Khan S, et al. Annu Rev Biochem. 1997;66:785-805. doi: 10.1146/annurev.biochem.66.1.785. Annu Rev Biochem. 1997. PMID: 9242924 Review.
Overexpression of MAP4 inhibits organelle motility and trafficking in vivo.
Bulinski JC, McGraw TE, Gruber D, Nguyen HL, Sheetz MP. Bulinski JC, et al. J Cell Sci. 1997 Dec;110 ( Pt 24):3055-64. J Cell Sci. 1997. PMID: 9365275
Cell migration: regulation of force on extracellular-matrix-integrin complexes.
Sheetz MP, Felsenfeld DP, Galbraith CG. Sheetz MP, et al. Trends Cell Biol. 1998 Feb;8(2):51-4. doi: 10.1016/s0962-8924(98)80005-6. Trends Cell Biol. 1998. PMID: 9695809 Review.
Forces on adhesive contacts affect cell function.
Galbraith CG, Sheetz MP. Galbraith CG, et al. Curr Opin Cell Biol. 1998 Oct;10(5):566-71. doi: 10.1016/s0955-0674(98)80030-6. Curr Opin Cell Biol. 1998. PMID: 9818165 Review.
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