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The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space.
Klughammer J, Kiesel B, Roetzer T, Fortelny N, Nemc A, Nenning KH, Furtner J, Sheffield NC, Datlinger P, Peter N, Nowosielski M, Augustin M, Mischkulnig M, Ströbel T, Alpar D, Ergüner B, Senekowitsch M, Moser P, Freyschlag CF, Kerschbaumer J, Thomé C, Grams AE, Stockhammer G, Kitzwoegerer M, Oberndorfer S, Marhold F, Weis S, Trenkler J, Buchroithner J, Pichler J, Haybaeck J, Krassnig S, Mahdy Ali K, von Campe G, Payer F, Sherif C, Preiser J, Hauser T, Winkler PA, Kleindienst W, Würtz F, Brandner-Kokalj T, Stultschnig M, Schweiger S, Dieckmann K, Preusser M, Langs G, Baumann B, Knosp E, Widhalm G, Marosi C, Hainfellner JA, Woehrer A, Bock C. Klughammer J, et al. Among authors: sheffield nc. Nat Med. 2018 Oct;24(10):1611-1624. doi: 10.1038/s41591-018-0156-x. Epub 2018 Aug 27. Nat Med. 2018. PMID: 30150718 Free PMC article.
Multi-Omics of Single Cells: Strategies and Applications.
Bock C, Farlik M, Sheffield NC. Bock C, et al. Among authors: sheffield nc. Trends Biotechnol. 2016 Aug;34(8):605-608. doi: 10.1016/j.tibtech.2016.04.004. Epub 2016 May 20. Trends Biotechnol. 2016. PMID: 27212022 Free PMC article.
Differential DNA Methylation Analysis without a Reference Genome.
Klughammer J, Datlinger P, Printz D, Sheffield NC, Farlik M, Hadler J, Fritsch G, Bock C. Klughammer J, et al. Among authors: sheffield nc. Cell Rep. 2015 Dec 22;13(11):2621-2633. doi: 10.1016/j.celrep.2015.11.024. Epub 2015 Dec 8. Cell Rep. 2015. PMID: 26673328 Free PMC article.
Coloc-stats: a unified web interface to perform colocalization analysis of genomic features.
Simovski B, Kanduri C, Gundersen S, Titov D, Domanska D, Bock C, Bossini-Castillo L, Chikina M, Favorov A, Layer RM, Mironov AA, Quinlan AR, Sheffield NC, Trynka G, Sandve GK. Simovski B, et al. Among authors: sheffield nc. Nucleic Acids Res. 2018 Jul 2;46(W1):W186-W193. doi: 10.1093/nar/gky474. Nucleic Acids Res. 2018. PMID: 29873782 Free PMC article.
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