Shelat A - Search Results

1

High-throughput assays for promiscuous inhibitors.

Feng BY, Shelat A, Doman TN, Guy RK, Shoichet BK. Feng BY, et al. Among authors: shelat a. Nat Chem Biol. 2005 Aug;1(3):146-8. doi: 10.1038/nchembio718. Epub 2005 Jul 3. Nat Chem Biol. 2005. PMID: 16408018

2

Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators.

Arnold LA, Estébanez-Perpiñá E, Togashi M, Jouravel N, Shelat A, McReynolds AC, Mar E, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK. Arnold LA, et al. Among authors: shelat a. J Biol Chem. 2005 Dec 30;280(52):43048-55. doi: 10.1074/jbc.M506693200. Epub 2005 Oct 31. J Biol Chem. 2005. PMID: 16263725

3

Discovery of trypanocidal compounds by whole cell HTS of Trypanosoma brucei.

Mackey ZB, Baca AM, Mallari JP, Apsel B, Shelat A, Hansell EJ, Chiang PK, Wolff B, Guy KR, Williams J, McKerrow JH. Mackey ZB, et al. Among authors: shelat a. Chem Biol Drug Des. 2006 May;67(5):355-63. doi: 10.1111/j.1747-0285.2006.00389.x. Chem Biol Drug Des. 2006. PMID: 16784460

4

A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding.

Arnold LA, Estébanez-Perpiñá E, Togashi M, Shelat A, Ocasio CA, McReynolds AC, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK. Arnold LA, et al. Among authors: shelat a. Sci STKE. 2006 Jun 27;2006(341):pl3. doi: 10.1126/stke.3412006pl3. Sci STKE. 2006. PMID: 16804159

5

Searching for new antimalarial therapeutics amongst known drugs.

Weisman JL, Liou AP, Shelat AA, Cohen FE, Guy RK, DeRisi JL. Weisman JL, et al. Among authors: shelat aa. Chem Biol Drug Des. 2006 Jun;67(6):409-16. doi: 10.1111/j.1747-0285.2006.00391.x. Chem Biol Drug Des. 2006. PMID: 16882315 Free PMC article.

6

The interdependence between screening methods and screening libraries.

Shelat AA, Guy RK. Shelat AA, et al. Curr Opin Chem Biol. 2007 Jun;11(3):244-51. doi: 10.1016/j.cbpa.2007.05.003. Epub 2007 May 23. Curr Opin Chem Biol. 2007. PMID: 17524728 Review.

7

Scaffold composition and biological relevance of screening libraries.

Shelat AA, Guy RK. Shelat AA, et al. Nat Chem Biol. 2007 Aug;3(8):442-6. doi: 10.1038/nchembio0807-442. Nat Chem Biol. 2007. PMID: 17637770

8

Assay Optimization and Screening of RNA-Protein Interactions by AlphaScreen.

Mills NL, Shelat AA, Guy RK. Mills NL, et al. Among authors: shelat aa. J Biomol Screen. 2007 Oct;12(7):946-55. doi: 10.1177/1087057107306128. J Biomol Screen. 2007. PMID: 17942787

9

Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

Mallari JP, Shelat AA, Obrien T, Caffrey CR, Kosinski A, Connelly M, Harbut M, Greenbaum D, McKerrow JH, Guy RK. Mallari JP, et al. Among authors: shelat aa. J Med Chem. 2008 Feb 14;51(3):545-52. doi: 10.1021/jm070760l. Epub 2008 Jan 4. J Med Chem. 2008. PMID: 18173229

10

A road less traveled by: exploring a decade of Ellman chemistry.

Shelat AA, Guy RK. Shelat AA, et al. Bioorg Med Chem. 2009 Feb 1;17(3):1088-93. doi: 10.1016/j.bmc.2008.02.087. Epub 2008 Mar 4. Bioorg Med Chem. 2009. PMID: 18343129 Free PMC article.

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