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High population frequencies of APOL1 risk variants are associated with increased prevalence of non-diabetic chronic kidney disease in the Igbo people from south-eastern Nigeria.
Ulasi II, Tzur S, Wasser WG, Shemer R, Kruzel E, Feigin E, Ijoma CK, Onodugo OD, Okoye JU, Arodiwe EB, Ifebunandu NA, Chukwuka CJ, Onyedum CC, Ijoma UN, Nna E, Onuigbo M, Rosset S, Skorecki K. Ulasi II, et al. Among authors: shemer r. Nephron Clin Pract. 2013;123(1-2):123-8. doi: 10.1159/000353223. Epub 2013 Jul 13. Nephron Clin Pract. 2013. PMID: 23860441
APOL1-Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes.
Kruzel-Davila E, Shemer R, Ofir A, Bavli-Kertselli I, Darlyuk-Saadon I, Oren-Giladi P, Wasser WG, Magen D, Zaknoun E, Schuldiner M, Salzberg A, Kornitzer D, Marelja Z, Simons M, Skorecki K. Kruzel-Davila E, et al. Among authors: shemer r. J Am Soc Nephrol. 2017 Apr;28(4):1117-1130. doi: 10.1681/ASN.2016050546. Epub 2016 Nov 18. J Am Soc Nephrol. 2017. PMID: 27864431 Free PMC article.
A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy.
Skorecki KL, Lee JH, Langefeld CD, Rosset S, Tzur S, Wasser WG, Shemer R, Hawkins GA, Divers J, Parekh RS, Li M, Sampson MG, Kretzler M, Pollak MR, Shah S, Blackler D, Nichols B, Wilmot M, Alper SL, Freedman BI, Friedman DJ. Skorecki KL, et al. Among authors: shemer r. Nephrol Dial Transplant. 2018 Feb 1;33(2):323-330. doi: 10.1093/ndt/gfw451. Nephrol Dial Transplant. 2018. PMID: 28339911 Free PMC article.
G1 is the major APOL1 risk allele for hypertension-attributed nephropathy in Central Africa.
Sumaili EK, Shemer R, Kruzel-Davila E, Cohen EP, Mutantu PN, Bukabau JB, Makulo JRR, Mokoli VM, Luse JL, Pakasa NM, Cavalier E, Wumba RD, Reiner-Benaim A, Boner G, Lifschitz M, Nseka NM, Skorecki K, Wasser WG. Sumaili EK, et al. Among authors: shemer r. Clin Kidney J. 2018 Oct 9;12(2):188-195. doi: 10.1093/ckj/sfy073. eCollection 2019 Apr. Clin Kidney J. 2018. PMID: 30976395 Free PMC article.
KRT14 haploinsufficiency results in increased susceptibility of keratinocytes to TNF-alpha-induced apoptosis and causes Naegeli-Franceschetti-Jadassohn syndrome.
Lugassy J, McGrath JA, Itin P, Shemer R, Verbov J, Murphy HR, Ishida-Yamamoto A, Digiovanna JJ, Bercovich D, Karin N, Vitenshtein A, Uitto J, Bergman R, Richard G, Sprecher E. Lugassy J, et al. Among authors: shemer r. J Invest Dermatol. 2008 Jun;128(6):1517-24. doi: 10.1038/sj.jid.5701187. Epub 2007 Nov 29. J Invest Dermatol. 2008. PMID: 18049449
Coevolution of cyclin Pcl5 and its substrate Gcn4.
Gildor T, Shemer R, Atir-Lande A, Kornitzer D. Gildor T, et al. Among authors: shemer r. Eukaryot Cell. 2005 Feb;4(2):310-8. doi: 10.1128/EC.4.2.310-318.2005. Eukaryot Cell. 2005. PMID: 15701793 Free PMC article.
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