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SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution.
Zahradník J, Marciano S, Shemesh M, Zoler E, Harari D, Chiaravalli J, Meyer B, Rudich Y, Li C, Marton I, Dym O, Elad N, Lewis MG, Andersen H, Gagne M, Seder RA, Douek DC, Schreiber G. Zahradník J, et al. Among authors: shemesh m. Nat Microbiol. 2021 Sep;6(9):1188-1198. doi: 10.1038/s41564-021-00954-4. Epub 2021 Aug 16. Nat Microbiol. 2021. PMID: 34400835
De novo developed protein binders mimicking Interferon lambda signaling.
Kolářová L, Zahradník J, Huličiak M, Mikulecký P, Peleg Y, Shemesh M, Schreiber G, Schneider B. Kolářová L, et al. Among authors: shemesh m. FEBS J. 2022 May;289(9):2672-2684. doi: 10.1111/febs.16300. Epub 2021 Dec 7. FEBS J. 2022. PMID: 34826176 Free article.
Correction: SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon.
Shemesh M, Aktepe TE, Deerain JM, McAuley JL, Audsley MD, David CT, Purcell DFJ, Urin V, Hartmann R, Moseley GW, Mackenzie JM, Schreiber G, Harari D. Shemesh M, et al. PLoS Pathog. 2021 Dec 10;17(12):e1010146. doi: 10.1371/journal.ppat.1010146. eCollection 2021 Dec. PLoS Pathog. 2021. PMID: 34890433 Free PMC article.
Anti-SARS-CoV-2 immunoadhesin remains effective against Omicron and other emerging variants of concern.
Cohen-Dvashi H, Weinstein J, Katz M, Eilon-Ashkenazy M, Mor Y, Shimon A, Achdout H, Tamir H, Israely T, Strobelt R, Shemesh M, Stoler-Barak L, Shulman Z, Paran N, Fleishman SJ, Diskin R. Cohen-Dvashi H, et al. Among authors: shemesh m. iScience. 2022 Oct 21;25(10):105193. doi: 10.1016/j.isci.2022.105193. Epub 2022 Sep 28. iScience. 2022. PMID: 36188189 Free PMC article.
A social chemosignaling function for human handshaking.
Frumin I, Perl O, Endevelt-Shapira Y, Eisen A, Eshel N, Heller I, Shemesh M, Ravia A, Sela L, Arzi A, Sobel N. Frumin I, et al. Among authors: shemesh m. Elife. 2015 Mar 3;4:e05154. doi: 10.7554/eLife.05154. Elife. 2015. PMID: 25732039 Free PMC article.
186 results