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Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.
Yuan P, Ito K, Perez-Lorenzo R, Del Guzzo C, Lee JH, Shen CH, Bosenberg MW, McMahon M, Cantley LC, Zheng B. Yuan P, et al. Among authors: shen ch. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18226-31. doi: 10.1073/pnas.1317577110. Epub 2013 Oct 21. Proc Natl Acad Sci U S A. 2013. PMID: 24145418 Free PMC article.
Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis.
Casimiro MC, Di Sante G, Di Rocco A, Loro E, Pupo C, Pestell TG, Bisetto S, Velasco-Velázquez MA, Jiao X, Li Z, Kusminski CM, Seifert EL, Wang C, Ly D, Zheng B, Shen CH, Scherer PE, Pestell RG. Casimiro MC, et al. Among authors: shen ch. Cancer Res. 2017 Jul 1;77(13):3391-3405. doi: 10.1158/0008-5472.CAN-16-0425. Epub 2017 May 18. Cancer Res. 2017. PMID: 28522753 Free PMC article.
STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming.
Chu Z, Gu L, Hu Y, Zhang X, Li M, Chen J, Teng D, Huang M, Shen CH, Cai L, Yoshida T, Qi Y, Niu Z, Feng A, Geng S, Frederick DT, Specht E, Piris A, Sullivan RJ, Flaherty KT, Boland GM, Georgopoulos K, Liu D, Shi Y, Zheng B. Chu Z, et al. Among authors: shen ch. Nat Commun. 2022 Apr 6;13(1):1859. doi: 10.1038/s41467-022-29541-9. Nat Commun. 2022. PMID: 35388001 Free PMC article.
Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis.
Yuan P, Teng D, de Groot E, Li M, Trousil S, Shen CH, Roszik J, Davies MA, Gopal YNV, Zheng B. Yuan P, et al. Among authors: shen ch. iScience. 2023 Apr 29;26(6):106791. doi: 10.1016/j.isci.2023.106791. eCollection 2023 Jun 16. iScience. 2023. PMID: 37213225 Free PMC article.
591 results