Shen D - Search Results

1

Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release.

Shen D, Wang X, Li X, Zhang X, Yao Z, Dibble S, Dong XP, Yu T, Lieberman AP, Showalter HD, Xu H. Shen D, et al. Nat Commun. 2012 Mar 13;3:731. doi: 10.1038/ncomms1735. Nat Commun. 2012. PMID: 22415822 Free PMC article.

2

Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis.

Dong XP, Wang X, Shen D, Chen S, Liu M, Wang Y, Mills E, Cheng X, Delling M, Xu H. Dong XP, et al. Among authors: shen d. J Biol Chem. 2009 Nov 13;284(46):32040-52. doi: 10.1074/jbc.M109.037184. Epub 2009 Jul 28. J Biol Chem. 2009. PMID: 19638346 Free PMC article.

3

PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome.

Dong XP, Shen D, Wang X, Dawson T, Li X, Zhang Q, Cheng X, Zhang Y, Weisman LS, Delling M, Xu H. Dong XP, et al. Among authors: shen d. Nat Commun. 2010 Jul 13;1(4):38. doi: 10.1038/ncomms1037. Nat Commun. 2010. PMID: 20802798 Free PMC article.

4

Pairing phosphoinositides with calcium ions in endolysosomal dynamics: phosphoinositides control the direction and specificity of membrane trafficking by regulating the activity of calcium channels in the endolysosomes.

Shen D, Wang X, Xu H. Shen D, et al. Bioessays. 2011 Jun;33(6):448-57. doi: 10.1002/bies.201000152. Epub 2011 Apr 28. Bioessays. 2011. PMID: 21538413 Free PMC article. Review.

5

Ryanodine receptor antagonists adapt NPC1 proteostasis to ameliorate lipid storage in Niemann-Pick type C disease fibroblasts.

Yu T, Chung C, Shen D, Xu H, Lieberman AP. Yu T, et al. Among authors: shen d. Hum Mol Genet. 2012 Jul 15;21(14):3205-14. doi: 10.1093/hmg/dds145. Epub 2012 Apr 14. Hum Mol Genet. 2012. PMID: 22505584 Free PMC article.

6

Mucolipins: Intracellular TRPML1-3 channels.

Cheng X, Shen D, Samie M, Xu H. Cheng X, et al. Among authors: shen d. FEBS Lett. 2010 May 17;584(10):2013-21. doi: 10.1016/j.febslet.2009.12.056. Epub 2010 Jan 13. FEBS Lett. 2010. PMID: 20074572 Free PMC article. Review.

7

TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation.

Cheng X, Jin J, Hu L, Shen D, Dong XP, Samie MA, Knoff J, Eisinger B, Liu ML, Huang SM, Caterina MJ, Dempsey P, Michael LE, Dlugosz AA, Andrews NC, Clapham DE, Xu H. Cheng X, et al. Among authors: shen d. Cell. 2010 Apr 16;141(2):331-43. doi: 10.1016/j.cell.2010.03.013. Cell. 2010. PMID: 20403327 Free PMC article.

8

TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes.

Wang X, Zhang X, Dong XP, Samie M, Li X, Cheng X, Goschka A, Shen D, Zhou Y, Harlow J, Zhu MX, Clapham DE, Ren D, Xu H. Wang X, et al. Among authors: shen d. Cell. 2012 Oct 12;151(2):372-83. doi: 10.1016/j.cell.2012.08.036. Cell. 2012. PMID: 23063126 Free PMC article.

9

KHDRBS1 as a novel prognostic signaling biomarker influencing hepatocellular carcinoma cell proliferation, migration, immune microenvironment, and drug sensitivity.

Fan R, Liu F, Gong Q, Liu D, Tang S, Shen D. Fan R, et al. Among authors: shen d. Front Immunol. 2024 Apr 10;15:1393801. doi: 10.3389/fimmu.2024.1393801. eCollection 2024. Front Immunol. 2024. PMID: 38660302 Free PMC article.

10

Identification and characterization of emGalaseE, a β-1,4 galactosidase from Elizabethkingia meningoseptica, and its application on living cell surface.

Tong Y, Lu X, Shen D, Rao L, Zou L, Lyu S, Hou L, Sun G, Chen L. Tong Y, et al. Among authors: shen d. Int J Biol Macromol. 2024 Apr 22:131766. doi: 10.1016/j.ijbiomac.2024.131766. Online ahead of print. Int J Biol Macromol. 2024. PMID: 38657932

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