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SU086, an inhibitor of HSP90, impairs glycolysis and represents a treatment strategy for advanced prostate cancer.
Rice MA, Kumar V, Tailor D, Garcia-Marques FJ, Hsu EC, Liu S, Bermudez A, Kanchustambham V, Shankar V, Inde Z, Alabi BR, Muruganantham A, Shen M, Pandrala M, Nolley R, Aslan M, Ghoochani A, Agarwal A, Buckup M, Kumar M, Going CC, Peehl DM, Dixon SJ, Zare RN, Brooks JD, Pitteri SJ, Malhotra SV, Stoyanova T. Rice MA, et al. Among authors: shen m. Cell Rep Med. 2022 Feb 2;3(2):100502. doi: 10.1016/j.xcrm.2021.100502. eCollection 2022 Feb 15. Cell Rep Med. 2022. PMID: 35243415 Free PMC article.
Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1.
Hsu EC, Rice MA, Bermudez A, Marques FJG, Aslan M, Liu S, Ghoochani A, Zhang CA, Chen YS, Zlitni A, Kumar S, Nolley R, Habte F, Shen M, Koul K, Peehl DM, Zoubeidi A, Gambhir SS, Kunder CA, Pitteri SJ, Brooks JD, Stoyanova T. Hsu EC, et al. Among authors: shen m. Proc Natl Acad Sci U S A. 2020 Jan 28;117(4):2032-2042. doi: 10.1073/pnas.1905384117. Epub 2020 Jan 13. Proc Natl Acad Sci U S A. 2020. PMID: 31932422 Free PMC article.
Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer.
Liu S, Shen M, Hsu EC, Zhang CA, Garcia-Marques F, Nolley R, Koul K, Rice MA, Aslan M, Pitteri SJ, Massie C, George A, Brooks JD, Gnanapragasam VJ, Stoyanova T. Liu S, et al. Among authors: shen m. Br J Cancer. 2021 Mar;124(5):896-900. doi: 10.1038/s41416-020-01200-0. Epub 2020 Dec 8. Br J Cancer. 2021. PMID: 33288843 Free PMC article.
MCM2-7 complex is a novel druggable target for neuroendocrine prostate cancer.
Hsu EC, Shen M, Aslan M, Liu S, Kumar M, Garcia-Marques F, Nguyen HM, Nolley R, Pitteri SJ, Corey E, Brooks JD, Stoyanova T. Hsu EC, et al. Among authors: shen m. Sci Rep. 2021 Jun 25;11(1):13305. doi: 10.1038/s41598-021-92552-x. Sci Rep. 2021. PMID: 34172788 Free PMC article.
Oncogene-mediated metabolic gene signature predicts breast cancer outcome.
Aslan M, Hsu EC, Garcia-Marques FJ, Bermudez A, Liu S, Shen M, West M, Zhang CA, Rice MA, Brooks JD, West R, Pitteri SJ, Győrffy B, Stoyanova T. Aslan M, et al. Among authors: shen m. NPJ Breast Cancer. 2021 Oct 28;7(1):141. doi: 10.1038/s41523-021-00341-6. NPJ Breast Cancer. 2021. PMID: 34711841 Free PMC article.
ACAA2 is a novel molecular indicator for cancers with neuroendocrine phenotype.
Shen M, Liu S, Toland A, Hsu EC, Hartono AB, Alabi BR, Aslan M, Nguyen HM, Sessions CJ, Nolley R, Shi C, Huang J, Brooks JD, Corey E, Stoyanova T. Shen M, et al. Br J Cancer. 2023 Nov;129(11):1818-1828. doi: 10.1038/s41416-023-02448-y. Epub 2023 Oct 5. Br J Cancer. 2023. PMID: 37798372 Free PMC article.
High expression of Trop2 is associated with aggressive localized prostate cancer and is a candidate urinary biomarker.
Liu S, Hawley SJ, Kunder CA, Hsu EC, Shen M, Westphalen L, Auman H, Newcomb LF, Lin DW, Nelson PS, Feng Z, Tretiakova MS, True LD, Vakar-Lopez F, Carroll PR, Simko J, Gleave ME, Troyer DA, McKenney JK, Brooks JD, Liss MA, Stoyanova T. Liu S, et al. Among authors: shen m. Sci Rep. 2024 Jan 4;14(1):486. doi: 10.1038/s41598-023-50215-z. Sci Rep. 2024. PMID: 38177207 Free PMC article.
6,419 results