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Page 1
Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer's disease.
van Olst L, Simonton B, Edwards AJ, Forsyth AV, Boles J, Jamshidi P, Watson T, Shepard N, Krainc T, Argue BM, Zhang Z, Kuruvilla J, Camp L, Li M, Xu H, Norman JL, Cahan J, Vassar R, Chen J, Castellani RJ, Nicoll JA, Boche D, Gate D. van Olst L, et al. Among authors: shepard n. Nat Med. 2025 May;31(5):1604-1616. doi: 10.1038/s41591-025-03574-1. Epub 2025 Mar 6. Nat Med. 2025. PMID: 40050704 Free PMC article.
Author Correction: Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer's disease.
van Olst L, Simonton B, Edwards AJ, Forsyth AV, Boles J, Jamshidi P, Watson T, Shepard N, Krainc T, Argue BM, Zhang Z, Kuruvilla J, Camp L, Li M, Xu H, Norman JL, Cahan J, Vassar R, Chen J, Castellani RJ, Nicoll JA, Boche D, Gate D. van Olst L, et al. Among authors: shepard n. Nat Med. 2025 May;31(5):1712. doi: 10.1038/s41591-025-03664-0. Nat Med. 2025. PMID: 40155563 Free PMC article. No abstract available.
LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons.
Chen C, Masotti M, Shepard N, Promes V, Tombesi G, Arango D, Manzoni C, Greggio E, Hilfiker S, Kozorovitskiy Y, Parisiadou L. Chen C, et al. Among authors: shepard n. bioRxiv [Preprint]. 2024 Jun 8:2024.06.06.597594. doi: 10.1101/2024.06.06.597594. bioRxiv. 2024. Update in: Mol Psychiatry. 2025 Oct;30(10):4473-4486. doi: 10.1038/s41380-025-03030-z. PMID: 38895420 Free PMC article. Updated. Preprint.
Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder.
Song BJ, Ge Y, Nicolella A, Kwon MJ, Lodder B, Bonanno K, Valle-Tojeiro A, Hartley ND, Perzel Mandell K, Adeleye J, Misri D, Geng C, Natarajan S, Picard I, Shepard N, Hall A, Tian J, Aryal S, Farsi Z, Liu XM, Morshed N, Nadaf NM, Pribiag H, Simmons SK, Mani DR, Stevens B, Kunwar PS, Fu Z, Macosko EZ, Levin JZ, Sabatini BL, Carr SA, Dejanovic B, Keshishian H, Granger AJ, Sheng M. Song BJ, et al. Among authors: shepard n. Nat Commun. 2025 Nov 28;16(1):10793. doi: 10.1038/s41467-025-66504-2. Nat Commun. 2025. PMID: 41315276 Free PMC article.
Meta-analysis of the brain transcriptomes of multiple genetic mouse models of schizophrenia highlights dysregulation in striatum and thalamus.
Perzel Mandell KA, Simmons SK, Nadig A, Farsi Z, Huang WC, Aryal S, Kwon MJ, Song B, Brenner K, Shepard N, Nicolella AA, O'Brien LD, Lichtman AH, Levin JZ, Sheng M. Perzel Mandell KA, et al. Among authors: shepard n. Transl Psychiatry. 2025 Sep 29;15(1):345. doi: 10.1038/s41398-025-03563-5. Transl Psychiatry. 2025. PMID: 41022686 Free PMC article.
MapMyCells: High-performance mapping of unlabeled cell-by-gene data to reference brain taxonomies.
Daniel SF, Lee C, Mollenkopf T, Lee M, Arbuckle J, Fiabane E, Gabitto MI, Johansen N, Kapen I, Kraft AW, Lai J, Li SY, McGinty R, Miller JA, Welch-Moosman S, Otto S, Sawyer L, Shepard N, Thompson CL, Tjärnberg A, Waters J, Zhen X, Macosko E, Lein ES, Ng L, Zeng H, Mufti S, Yao Z, Hawrylycz MJ. Daniel SF, et al. Among authors: shepard n. bioRxiv [Preprint]. 2026 Mar 9:2026.03.06.710160. doi: 10.64898/2026.03.06.710160. bioRxiv. 2026. PMID: 41958981 Free PMC article. Preprint.
Aberrant mRNA splicing and impaired hippocampal neurogenesis in Grin2b mutant mice.
Farsi Z, Nicolella A, Simmons SK, Shin W, Kang M, Lee G, Kwon MJ, Brenner KS, Picard I, Shepard N, Misri D, Perzel Mandell KA, Levin JZ, Kim E, Sheng M. Farsi Z, et al. Among authors: shepard n. iScience. 2026 Jan 15;29(2):114700. doi: 10.1016/j.isci.2026.114700. eCollection 2026 Feb 20. iScience. 2026. PMID: 41675057 Free PMC article.
Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder.
Song BJ, Ge Y, Nicolella A, Kwon MJ, Lodder B, Bonanno K, Valle-Tojeiro A, Hartley ND, Mandell KP, Adeleye J, Misri D, Geng C, Natarajan S, Picard I, Shepard N, Hall A, Tian J, Aryal S, Farsi Z, Liu XM, Morshed N, Nadaf NM, Pribiag H, Simmons SK, Mani DR, Stevens B, Kunwar PS, Fu Z, Macosko EZ, Levin JZ, Sabatini BL, Carr SA, Dejanovic B, Keshishian H, Granger AJ, Sheng M. Song BJ, et al. Among authors: shepard n. bioRxiv [Preprint]. 2025 Nov 22:2024.09.24.614783. doi: 10.1101/2024.09.24.614783. bioRxiv. 2025. Update in: Nat Commun. 2025 Nov 28;16(1):10793. doi: 10.1038/s41467-025-66504-2. PMID: 41332738 Free PMC article. Updated. Preprint.
189 results