Sher A - Search Results

1

Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases).

Taylor GA, Feng CG, Sher A. Taylor GA, et al. Among authors: sher a. Microbes Infect. 2007 Nov-Dec;9(14-15):1644-51. doi: 10.1016/j.micinf.2007.09.004. Epub 2007 Sep 14. Microbes Infect. 2007. PMID: 18023232 Free article. Review.

2

Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP.

Taylor GA, Collazo CM, Yap GS, Nguyen K, Gregorio TA, Taylor LS, Eagleson B, Secrest L, Southon EA, Reid SW, Tessarollo L, Bray M, McVicar DW, Komschlies KL, Young HA, Biron CA, Sher A, Vande Woude GF. Taylor GA, et al. Among authors: sher a. Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):751-5. doi: 10.1073/pnas.97.2.751. Proc Natl Acad Sci U S A. 2000. PMID: 10639151 Free PMC article.

3

Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection.

Collazo CM, Yap GS, Sempowski GD, Lusby KC, Tessarollo L, Vande Woude GF, Sher A, Taylor GA. Collazo CM, et al. Among authors: sher a. J Exp Med. 2001 Jul 16;194(2):181-8. doi: 10.1084/jem.194.2.181. J Exp Med. 2001. PMID: 11457893 Free PMC article.

4

Transgenic mice expressing human interleukin-10 in the antigen-presenting cell compartment show increased susceptibility to infection with Mycobacterium avium associated with decreased macrophage effector function and apoptosis.

Feng CG, Kullberg MC, Jankovic D, Cheever AW, Caspar P, Coffman RL, Sher A. Feng CG, et al. Among authors: sher a. Infect Immun. 2002 Dec;70(12):6672-9. doi: 10.1128/IAI.70.12.6672-6679.2002. Infect Immun. 2002. PMID: 12438341 Free PMC article.

5

The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments.

Collazo CM, Yap GS, Hieny S, Caspar P, Feng CG, Taylor GA, Sher A. Collazo CM, et al. Among authors: sher a. Infect Immun. 2002 Dec;70(12):6933-9. doi: 10.1128/IAI.70.12.6933-6939.2002. Infect Immun. 2002. PMID: 12438372 Free PMC article.

6

A critical role for IL-21 in regulating immunoglobulin production.

Ozaki K, Spolski R, Feng CG, Qi CF, Cheng J, Sher A, Morse HC 3rd, Liu C, Schwartzberg PL, Leonard WJ. Ozaki K, et al. Among authors: sher a. Science. 2002 Nov 22;298(5598):1630-4. doi: 10.1126/science.1077002. Science. 2002. PMID: 12446913

7

Mice lacking myeloid differentiation factor 88 display profound defects in host resistance and immune responses to Mycobacterium avium infection not exhibited by Toll-like receptor 2 (TLR2)- and TLR4-deficient animals.

Feng CG, Scanga CA, Collazo-Custodio CM, Cheever AW, Hieny S, Caspar P, Sher A. Feng CG, et al. Among authors: sher a. J Immunol. 2003 Nov 1;171(9):4758-64. doi: 10.4049/jimmunol.171.9.4758. J Immunol. 2003. PMID: 14568952

8

Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia.

Feng CG, Collazo-Custodio CM, Eckhaus M, Hieny S, Belkaid Y, Elkins K, Jankovic D, Taylor GA, Sher A. Feng CG, et al. Among authors: sher a. J Immunol. 2004 Jan 15;172(2):1163-8. doi: 10.4049/jimmunol.172.2.1163. J Immunol. 2004. PMID: 14707092

9

MyD88-deficient mice display a profound loss in resistance to Mycobacterium tuberculosis associated with partially impaired Th1 cytokine and nitric oxide synthase 2 expression.

Scanga CA, Bafica A, Feng CG, Cheever AW, Hieny S, Sher A. Scanga CA, et al. Among authors: sher a. Infect Immun. 2004 Apr;72(4):2400-4. doi: 10.1128/IAI.72.4.2400-2404.2004. Infect Immun. 2004. PMID: 15039368 Free PMC article.

10

p47 GTPases: regulators of immunity to intracellular pathogens.

Taylor GA, Feng CG, Sher A. Taylor GA, et al. Among authors: sher a. Nat Rev Immunol. 2004 Feb;4(2):100-9. doi: 10.1038/nri1270. Nat Rev Immunol. 2004. PMID: 15040583 Review.

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