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Mature Purkinje cells require the retinoic acid-related orphan receptor-α (RORα) to maintain climbing fiber mono-innervation and other adult characteristics.
Chen XR, Heck N, Lohof AM, Rochefort C, Morel MP, Wehrlé R, Doulazmi M, Marty S, Cannaya V, Avci HX, Mariani J, Rondi-Reig L, Vodjdani G, Sherrard RM, Sotelo C, Dusart I. Chen XR, et al. Among authors: sherrard rm. J Neurosci. 2013 May 29;33(22):9546-62. doi: 10.1523/JNEUROSCI.2977-12.2013. J Neurosci. 2013. PMID: 23719821 Free PMC article.
Age-related Purkinje cell death is steroid dependent: RORα haplo-insufficiency impairs plasma and cerebellar steroids and Purkinje cell survival.
Janmaat S, Akwa Y, Doulazmi M, Bakouche J, Gautheron V, Liere P, Eychenne B, Pianos A, Luiten P, Groothuis T, Baulieu EE, Mariani J, Sherrard RM, Frédéric F. Janmaat S, et al. Among authors: sherrard rm. Age (Dordr). 2011 Dec;33(4):565-78. doi: 10.1007/s11357-010-9203-3. Epub 2011 Jan 11. Age (Dordr). 2011. PMID: 21222044 Free PMC article.
What does low-intensity rTMS do to the cerebellum?
Morellini N, Grehl S, Tang A, Rodger J, Mariani J, Lohof AM, Sherrard RM. Morellini N, et al. Among authors: sherrard rm. Cerebellum. 2015 Feb;14(1):23-6. doi: 10.1007/s12311-014-0617-9. Cerebellum. 2015. PMID: 25346177 Review.
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