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Architecture of the Trypanosoma brucei nucleus during interphase and mitosis.
Ogbadoyi E, Ersfeld K, Robinson D, Sherwin T, Gull K. Ogbadoyi E, et al. Chromosoma. 2000 Mar;108(8):501-13. doi: 10.1007/s004120050402. Chromosoma. 2000. PMID: 10794572
We also discuss the problems involved in chromosome segregation in the light of the fact that the T. brucei karyotype has 22 chromosomes in the apparent presence of only eight ultrastructurally defined kinetochores....
We also discuss the problems involved in chromosome segregation in the light of the fact that the T. brucei karyotype has 22 chromoso …
TbRab2p, a marker for the endoplasmic reticulum of Trypanosoma brucei, localises to the ERGIC in mammalian cells.
Field H, Ali BR, Sherwin T, Gull K, Croft SL, Field MC. Field H, et al. J Cell Sci. 1999 Jan;112 ( Pt 2):147-56. J Cell Sci. 1999. PMID: 9858468
Over expression of TbRab2p in procyclic form T. brucei results in a cell population having a 40-fold increase in TbRab2p expression. ...TbRab2p is therefore a new ER/ERGIC marker for T. brucei....
Over expression of TbRab2p in procyclic form T. brucei results in a cell population having a 40-fold increase in TbRab2p expression. …
Tubulin isotypes: generation of diversity in cells and microtubular organelles.
Gull K, Hussey PJ, Sasse R, Schneider A, Seebeck T, Sherwin T. Gull K, et al. J Cell Sci Suppl. 1986;5:243-55. doi: 10.1242/jcs.1986.supplement_5.16. J Cell Sci Suppl. 1986. PMID: 3477554
However, tubulin isotypes can also be generated by post-translational modifications and T. brucei utilizes two different modifications within one cell. ...
However, tubulin isotypes can also be generated by post-translational modifications and T. brucei utilizes two different modification …
Cell-cycle and developmental regulation of TbRAB31 localisation, a GTP-locked Rab protein from Trypanosoma brucei.
Field H, Sherwin T, Smith AC, Gull K, Field MC. Field H, et al. Mol Biochem Parasitol. 2000 Feb 25;106(1):21-35. doi: 10.1016/s0166-6851(99)00192-9. Mol Biochem Parasitol. 2000. PMID: 10743608
TbRAB31 is a constitutively expressed T. brucei Rab protein (formerly Trab7p) and is the product of one of two closely linked TbRAB genes, the other being TbRAB2 (TbRab2p, in: Field H, Ali BRS, Sherwin T, Gull K, Croft SL, Field MC. ...
TbRAB31 is a constitutively expressed T. brucei Rab protein (formerly Trab7p) and is the product of one of two closely linked TbRAB g …
Immunofluorescence of parasites.
Sherwin T, Read M. Sherwin T, et al. Methods Mol Biol. 1993;21:407-14. doi: 10.1385/0-89603-239-6:407. Methods Mol Biol. 1993. PMID: 8220731 No abstract available.
Visualization of detyrosination along single microtubules reveals novel mechanisms of assembly during cytoskeletal duplication in trypanosomes.
Sherwin T, Gull K. Sherwin T, et al. Cell. 1989 Apr 21;57(2):211-21. doi: 10.1016/0092-8674(89)90959-8. Cell. 1989. PMID: 2649249
We have been able to use immunogold labeling with monoclonal antibodies specific for tyrosinated alpha-tubulin to define new microtubule assembly within the T. brucei pellicular cytoskeleton. ...
We have been able to use immunogold labeling with monoclonal antibodies specific for tyrosinated alpha-tubulin to define new microtubule ass …
gamma-tubulin in trypanosomes: molecular characterisation and localisation to multiple and diverse microtubule organising centres.
Scott V, Sherwin T, Gull K. Scott V, et al. J Cell Sci. 1997 Jan;110 ( Pt 2):157-68. J Cell Sci. 1997. PMID: 9044046
In T. brucei gamma-tubulin is present in the basal bodies which subtend the flagellum and also at the anterior tip of the cell body where many minus ends of microtubules are located. ...
In T. brucei gamma-tubulin is present in the basal bodies which subtend the flagellum and also at the anterior tip of the cell body w …
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