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Lung deposition of droplet aerosols in monkeys.
Cheng YS, Irshad H, Kuehl P, Holmes TD, Sherwood R, Hobbs CH. Cheng YS, et al. Inhal Toxicol. 2008 Sep;20(11):1029-36. doi: 10.1080/08958370802105413. Inhal Toxicol. 2008. PMID: 18720170
Milestones in progression of primary pneumonic plague in cynomolgus macaques.
Koster F, Perlin DS, Park S, Brasel T, Gigliotti A, Barr E, Myers L, Layton RC, Sherwood R, Lyons CR. Koster F, et al. Infect Immun. 2010 Jul;78(7):2946-55. doi: 10.1128/IAI.01296-09. Epub 2010 Apr 12. Infect Immun. 2010. PMID: 20385751 Free PMC article.
Plazomicin is effective in a non-human primate pneumonic plague model.
Mega WM, Doyle-Eisele M, Cass RT, Kostrub CF, Sherwood RL, Metz MA, Cirz RT. Mega WM, et al. Bioorg Med Chem. 2016 Dec 15;24(24):6429-6439. doi: 10.1016/j.bmc.2016.08.049. Epub 2016 Aug 27. Bioorg Med Chem. 2016. PMID: 27614915
Protection in mice passively immunized with serum from cynomolgus macaques and humans vaccinated with recombinant plague vaccine (rF1V).
Fellows P, Adamovicz J, Hartings J, Sherwood R, Mega W, Brasel T, Barr E, Holland L, Lin W, Rom A, Blackwelder W, Price J, Morris S, Snow D, Hart MK. Fellows P, et al. Vaccine. 2010 Nov 16;28(49):7748-56. doi: 10.1016/j.vaccine.2010.09.062. Epub 2010 Oct 15. Vaccine. 2010. PMID: 20920572
Lethal factor, but not edema factor, is required to cause fatal anthrax in cynomolgus macaques after pulmonary spore challenge.
Hutt JA, Lovchik JA, Drysdale M, Sherwood RL, Brasel T, Lipscomb MF, Lyons CR. Hutt JA, et al. Am J Pathol. 2014 Dec;184(12):3205-16. doi: 10.1016/j.ajpath.2014.08.008. Epub 2014 Oct 5. Am J Pathol. 2014. PMID: 25285720 Free PMC article.
A plant-produced plague vaccine candidate confers protection to monkeys.
Mett V, Lyons J, Musiychuk K, Chichester JA, Brasil T, Couch R, Sherwood R, Palmer GA, Streatfield SJ, Yusibov V. Mett V, et al. Vaccine. 2007 Apr 20;25(16):3014-7. doi: 10.1016/j.vaccine.2007.01.017. Epub 2007 Jan 22. Vaccine. 2007. PMID: 17287055
Live attenuated Francisella novicida vaccine protects against Francisella tularensis pulmonary challenge in rats and non-human primates.
Chu P, Cunningham AL, Yu JJ, Nguyen JQ, Barker JR, Lyons CR, Wilder J, Valderas M, Sherwood RL, Arulanandam BP, Klose KE. Chu P, et al. PLoS Pathog. 2014 Oct 23;10(10):e1004439. doi: 10.1371/journal.ppat.1004439. eCollection 2014 Oct. PLoS Pathog. 2014. PMID: 25340543 Free PMC article.
Inhalational anthrax (Ames aerosol) in naïve and vaccinated New Zealand rabbits: characterizing the spread of bacteria from lung deposition to bacteremia.
Gutting BW, Nichols TL, Channel SR, Gearhart JM, Andrews GA, Berger AE, Mackie RS, Watson BJ, Taft SC, Overheim KA, Sherwood RL. Gutting BW, et al. Front Cell Infect Microbiol. 2012 Jun 28;2:87. doi: 10.3389/fcimb.2012.00087. eCollection 2012. Front Cell Infect Microbiol. 2012. PMID: 22919678 Free PMC article.
Modeling low-dose mortality and disease incubation period of inhalational anthrax in the rabbit.
Gutting BW, Marchette D, Sherwood R, Andrews GA, Director-Myska A, Channel SR, Wolfe D, Berger AE, Mackie RS, Watson BJ, Rukhin A. Gutting BW, et al. J Theor Biol. 2013 Jul 21;329:20-31. doi: 10.1016/j.jtbi.2013.03.020. Epub 2013 Apr 6. J Theor Biol. 2013. PMID: 23567649
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