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POU1F1-mediated activation of hGH-N by deoxyribonuclease I hypersensitive site II of the human growth hormone locus control region.
Hunsaker TL, Jefferson HS, Morrison JK, Franklin AJ, Shewchuk BM. Hunsaker TL, et al. J Mol Biol. 2012 Jan 6;415(1):29-45. doi: 10.1016/j.jmb.2011.11.001. Epub 2011 Nov 9. J Mol Biol. 2012. PMID: 22094313
Differential epigenetic and transcriptional response of the skeletal muscle carnitine palmitoyltransferase 1B (CPT1B) gene to lipid exposure with obesity.
Maples JM, Brault JJ, Witczak CA, Park S, Hubal MJ, Weber TM, Houmard JA, Shewchuk BM. Maples JM, et al. Among authors: shewchuk bm. Am J Physiol Endocrinol Metab. 2015 Aug 15;309(4):E345-56. doi: 10.1152/ajpendo.00505.2014. Epub 2015 Jun 9. Am J Physiol Endocrinol Metab. 2015. PMID: 26058865 Free PMC article.
Lipid exposure elicits differential responses in gene expression and DNA methylation in primary human skeletal muscle cells from severely obese women.
Maples JM, Brault JJ, Shewchuk BM, Witczak CA, Zou K, Rowland N, Hubal MJ, Weber TM, Houmard JA. Maples JM, et al. Among authors: shewchuk bm. Physiol Genomics. 2015 May;47(5):139-46. doi: 10.1152/physiolgenomics.00065.2014. Epub 2015 Feb 10. Physiol Genomics. 2015. PMID: 25670728 Free PMC article.
Notch-1 signaling is lost in prostate adenocarcinoma and promotes PTEN gene expression.
Whelan JT, Kellogg A, Shewchuk BM, Hewan-Lowe K, Bertrand FE. Whelan JT, et al. J Cell Biochem. 2009 Aug 1;107(5):992-1001. doi: 10.1002/jcb.22199. J Cell Biochem. 2009. PMID: 19479935
Growth hormone enhances LNCaP prostate cancer cell motility.
Nakonechnaya AO, Shewchuk BM. Nakonechnaya AO, et al. Among authors: shewchuk bm. Endocr Res. 2015;40(2):97-105. doi: 10.3109/07435800.2014.966383. Epub 2014 Oct 20. Endocr Res. 2015. PMID: 25330355
High Fat Diet Dysregulates Hypothalamic-Pituitary Axis Gene Expression Levels which are Differentially Rescued by EPA and DHA Ethyl Esters.
Shaikh SR, Shaver PR, Shewchuk BM. Shaikh SR, et al. Among authors: shewchuk bm. Mol Nutr Food Res. 2018 Jul;62(13):e1800219. doi: 10.1002/mnfr.201800219. Epub 2018 May 28. Mol Nutr Food Res. 2018. PMID: 29738112 Free PMC article.
Expression of Pit-1 in nonsomatotrope cell lines induces human growth hormone locus control region histone modification and hGH-N transcription.
Hogan KA, Jefferson HS, Karschner VA, Shewchuk BM. Hogan KA, et al. J Mol Biol. 2009 Jul 3;390(1):26-44. doi: 10.1016/j.jmb.2009.04.081. Epub 2009 May 7. J Mol Biol. 2009. PMID: 19427323
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