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K-ras mutation targeted to gastric tissue progenitor cells results in chronic inflammation, an altered microenvironment, and progression to intraepithelial neoplasia.
Okumura T, Ericksen RE, Takaishi S, Wang SS, Dubeykovskiy Z, Shibata W, Betz KS, Muthupalani S, Rogers AB, Fox JG, Rustgi AK, Wang TC. Okumura T, et al. Among authors: shibata w. Cancer Res. 2010 Nov 1;70(21):8435-45. doi: 10.1158/0008-5472.CAN-10-1506. Epub 2010 Oct 19. Cancer Res. 2010. PMID: 20959488 Free PMC article.
Inhibition of gastric carcinogenesis by the hormone gastrin is mediated by suppression of TFF1 epigenetic silencing.
Tomita H, Takaishi S, Menheniott TR, Yang X, Shibata W, Jin G, Betz KS, Kawakami K, Minamoto T, Tomasetto C, Rio MC, Lerkowit N, Varro A, Giraud AS, Wang TC. Tomita H, et al. Among authors: shibata w. Gastroenterology. 2011 Mar;140(3):879-91. doi: 10.1053/j.gastro.2010.11.037. Epub 2010 Nov 25. Gastroenterology. 2011. PMID: 21111741 Free PMC article.
Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche.
Hayakawa Y, Ariyama H, Stancikova J, Sakitani K, Asfaha S, Renz BW, Dubeykovskaya ZA, Shibata W, Wang H, Westphalen CB, Chen X, Takemoto Y, Kim W, Khurana SS, Tailor Y, Nagar K, Tomita H, Hara A, Sepulveda AR, Setlik W, Gershon MD, Saha S, Ding L, Shen Z, Fox JG, Friedman RA, Konieczny SF, Worthley DL, Korinek V, Wang TC. Hayakawa Y, et al. Among authors: shibata w. Cancer Cell. 2015 Dec 14;28(6):800-814. doi: 10.1016/j.ccell.2015.10.003. Epub 2015 Nov 12. Cancer Cell. 2015. PMID: 26585400 Free PMC article.
In vivo analysis of mouse gastrin gene regulation in enhanced GFP-BAC transgenic mice.
Takaishi S, Shibata W, Tomita H, Jin G, Yang X, Ericksen R, Dubeykovskaya Z, Asfaha S, Quante M, Betz KS, Shulkes A, Wang TC. Takaishi S, et al. Among authors: shibata w. Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G334-44. doi: 10.1152/ajpgi.00134.2010. Epub 2010 Nov 4. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21051525 Free PMC article.
100 results