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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2.
Shieh SY, Ikeda M, Taya Y, Prives C. Shieh SY, et al. Cell. 1997 Oct 31;91(3):325-34. doi: 10.1016/s0092-8674(00)80416-x. Cell. 1997. PMID: 9363941
Candidate tumor suppressor B-cell translocation gene 3 impedes neoplastic progression by suppression of AKT.
Cheng YC, Chen PH, Chiang HY, Suen CS, Hwang MJ, Lin TY, Yang HC, Lin WC, Lai PL, Shieh SY. Cheng YC, et al. Among authors: shieh sy. Cell Death Dis. 2015 Jan 8;6(1):e1584. doi: 10.1038/cddis.2014.550. Cell Death Dis. 2015. PMID: 25569101 Free PMC article.
The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1.
Yeh YH, Huang YF, Lin TY, Shieh SY. Yeh YH, et al. Among authors: shieh sy. Oncogene. 2009 Mar 12;28(10):1366-78. doi: 10.1038/onc.2008.477. Epub 2009 Jan 19. Oncogene. 2009. PMID: 19151762
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites.
Shieh SY, Ahn J, Tamai K, Taya Y, Prives C. Shieh SY, et al. Genes Dev. 2000 Feb 1;14(3):289-300. Genes Dev. 2000. PMID: 10673501 Free PMC article.
DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization.
Shieh SY, Taya Y, Prives C. Shieh SY, et al. EMBO J. 1999 Apr 1;18(7):1815-23. doi: 10.1093/emboj/18.7.1815. EMBO J. 1999. PMID: 10202145 Free PMC article.
A role for ATR in the DNA damage-induced phosphorylation of p53.
Tibbetts RS, Brumbaugh KM, Williams JM, Sarkaria JN, Cliby WA, Shieh SY, Taya Y, Prives C, Abraham RT. Tibbetts RS, et al. Among authors: shieh sy. Genes Dev. 1999 Jan 15;13(2):152-7. doi: 10.1101/gad.13.2.152. Genes Dev. 1999. PMID: 9925639 Free PMC article.
E1A signaling to p53 involves the p19(ARF) tumor suppressor.
de Stanchina E, McCurrach ME, Zindy F, Shieh SY, Ferbeyre G, Samuelson AV, Prives C, Roussel MF, Sherr CJ, Lowe SW. de Stanchina E, et al. Among authors: shieh sy. Genes Dev. 1998 Aug 1;12(15):2434-42. doi: 10.1101/gad.12.15.2434. Genes Dev. 1998. PMID: 9694807 Free PMC article.
p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner.
Ko LJ, Shieh SY, Chen X, Jayaraman L, Tamai K, Taya Y, Prives C, Pan ZQ. Ko LJ, et al. Among authors: shieh sy. Mol Cell Biol. 1997 Dec;17(12):7220-9. doi: 10.1128/mcb.17.12.7220. Mol Cell Biol. 1997. PMID: 9372954 Free PMC article.
Regulation of p53 after different forms of stress and at different cell cycle stages.
Gottifredi V, Shieh SY, Prives C. Gottifredi V, et al. Among authors: shieh sy. Cold Spring Harb Symp Quant Biol. 2000;65:483-8. doi: 10.1101/sqb.2000.65.483. Cold Spring Harb Symp Quant Biol. 2000. PMID: 12760065 Review. No abstract available.
Loss of the candidate tumor suppressor BTG3 triggers acute cellular senescence via the ERK-JMJD3-p16(INK4a) signaling axis.
Lin TY, Cheng YC, Yang HC, Lin WC, Wang CC, Lai PL, Shieh SY. Lin TY, et al. Among authors: shieh sy. Oncogene. 2012 Jul 5;31(27):3287-97. doi: 10.1038/onc.2011.491. Epub 2011 Oct 24. Oncogene. 2012. PMID: 22020331 Free article.
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