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Understanding Ras: 'it ain't over 'til it's over'.
Shields JM, Pruitt K, McFall A, Shaub A, Der CJ. Shields JM, et al. Trends Cell Biol. 2000 Apr;10(4):147-54. doi: 10.1016/s0962-8924(00)01740-2. Trends Cell Biol. 2000. PMID: 10740269 Review.
Similar nucleotide excision repair capacity in melanocytes and melanoma cells.
Gaddameedhi S, Kemp MG, Reardon JT, Shields JM, Smith-Roe SL, Kaufmann WK, Sancar A. Gaddameedhi S, et al. Among authors: shields jm. Cancer Res. 2010 Jun 15;70(12):4922-30. doi: 10.1158/0008-5472.CAN-10-0095. Epub 2010 May 25. Cancer Res. 2010. PMID: 20501836 Free PMC article.
Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK.
Sambade MJ, Camp JT, Kimple RJ, Sartor CI, Shields JM. Sambade MJ, et al. Among authors: shields jm. Radiother Oncol. 2009 Dec;93(3):639-44. doi: 10.1016/j.radonc.2009.09.006. Epub 2009 Oct 23. Radiother Oncol. 2009. PMID: 19853943 Free PMC article.
CD200 is induced by ERK and is a potential therapeutic target in melanoma.
Petermann KB, Rozenberg GI, Zedek D, Groben P, McKinnon K, Buehler C, Kim WY, Shields JM, Penland S, Bear JE, Thomas NE, Serody JS, Sharpless NE. Petermann KB, et al. Among authors: shields jm. J Clin Invest. 2007 Dec;117(12):3922-9. doi: 10.1172/JCI32163. J Clin Invest. 2007. PMID: 18008004 Free PMC article.
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