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An effective use of benzoic anhydride and its derivatives for the synthesis of carboxylic esters and lactones: a powerful and convenient mixed anhydride method promoted by basic catalysts.
Shiina I, Kubota M, Oshiumi H, Hashizume M. Shiina I, et al. J Org Chem. 2004 Mar 19;69(6):1822-30. doi: 10.1021/jo030367x. J Org Chem. 2004. PMID: 15058924
Total synthesis of buergerinin F via effective construction of the asymmetric quaternary carbons using an enantioselective aldol reaction.
Shiina I, Kawakita Y, Ibuka R, Yokoyama K, Yamai YS. Shiina I, et al. Chem Commun (Camb). 2005 Aug 28;(32):4062-4. doi: 10.1039/b507401k. Epub 2005 Jul 14. Chem Commun (Camb). 2005. PMID: 16091800
Enantioselective total synthesis of octalactin a using asymmetric aldol reactions and a rapid lactonization to form a medium-sized ring.
Shiina I, Hashizume M, Yamai YS, Oshiumi H, Shimazaki T, Takasuna YJ, Ibuka R. Shiina I, et al. Chemistry. 2005 Nov 4;11(22):6601-8. doi: 10.1002/chem.200500417. Chemistry. 2005. PMID: 16118824
Enantio- and diastereoselective total synthesis of EI-1941-1, -2, and -3, inhibitors of interleukin-1beta converting enzyme, and biological properties of their derivatives.
Shoji M, Uno T, Kakeya H, Onose R, Shiina I, Osada H, Hayashi Y. Shoji M, et al. J Org Chem. 2005 Nov 25;70(24):9905-15. doi: 10.1021/jo0516436. J Org Chem. 2005. PMID: 16292821
Stereoselective total synthesis of the proposed structure of 2-epibotcinolide.
Shiina I, Takasuna YJ, Suzuki RS, Oshiumi H, Komiyama Y, Hitomi S, Fukui H. Shiina I, et al. Org Lett. 2006 Nov 9;8(23):5279-82. doi: 10.1021/ol062058+. Org Lett. 2006. PMID: 17078697
Synthesis of the new pseudo-symmetrical tamoxifen derivatives and their anti-tumor activity.
Shiina I, Sano Y, Nakata K, Kikuchi T, Sasaki A, Ikekita M, Hasome Y. Shiina I, et al. Bioorg Med Chem Lett. 2007 May 1;17(9):2421-4. doi: 10.1016/j.bmcl.2007.02.037. Epub 2007 Feb 17. Bioorg Med Chem Lett. 2007. PMID: 17346960
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