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229 results
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The ATM gene and protein: possible roles in genome surveillance, checkpoint controls and cellular defence against oxidative stress.
Rotman G, Shiloh Y. Rotman G, et al. Among authors: shiloh y. Cancer Surv. 1997;29:285-304. Cancer Surv. 1997. PMID: 9338105 Review.
Amplification of c-myc and c-erbB-2 proto-oncogenes in human solid tumors: frequency and clinical significance.
Gutman M, Ravia Y, Assaf D, Yamamoto T, Rozin R, Shiloh Y. Gutman M, et al. Among authors: shiloh y. Int J Cancer. 1989 Nov 15;44(5):802-5. doi: 10.1002/ijc.2910440509. Int J Cancer. 1989. PMID: 2573579
Cellular and molecular characteristics of an immortalized ataxia-telangiectasia (group AB) cell line.
Ziv Y, Jaspers NG, Etkin S, Danieli T, Trakhtenbrot L, Amiel A, Ravia Y, Shiloh Y. Ziv Y, et al. Among authors: shiloh y. Cancer Res. 1989 May 1;49(9):2495-501. Cancer Res. 1989. PMID: 2539904
The defect in the AT-like hamster cell mutants is complemented by mouse chromosome 9 but not by any of the human chromosomes.
Jongmans W, Verhaegh GW, Jaspers NG, Demant P, Natarajan AT, Shiloh Y, Oshimura M, Stanbridge EJ, Athwal RS, Cuthbert AP, Newbold RF, Lohman PH, Zdzienicka MZ. Jongmans W, et al. Among authors: shiloh y. Mutat Res. 1996 Oct 18;364(2):91-102. doi: 10.1016/0921-8777(96)00027-4. Mutat Res. 1996. PMID: 8879275
Physical and genetic mapping at the ATA/ATC locus on chromosome 11q22-23.
Rotman G, Savitski K, Vanagaite L, Bar-Shira A, Ziv Y, Gilad S, Uchenik V, Smith S, Shiloh Y. Rotman G, et al. Among authors: shiloh y. Int J Radiat Biol. 1994 Dec;66(6 Suppl):S63-6. Int J Radiat Biol. 1994. PMID: 7836854
A high-density microsatellite map of the ataxia-telangiectasia locus.
Vanagaite L, James MR, Rotman G, Savitsky K, Bar-Shira A, Gilad S, Ziv Y, Uchenik V, Sartiel A, Collins FS, Sheffield VC, Richard CW 3rd, Weissenbach J, Shiloh Y. Vanagaite L, et al. Among authors: shiloh y. Hum Genet. 1995 Apr;95(4):451-4. doi: 10.1007/BF00208975. Hum Genet. 1995. PMID: 7705845
A single ataxia telangiectasia gene with a product similar to PI-3 kinase.
Savitsky K, Bar-Shira A, Gilad S, Rotman G, Ziv Y, Vanagaite L, Tagle DA, Smith S, Uziel T, Sfez S, Ashkenazi M, Pecker I, Frydman M, Harnik R, Patanjali SR, Simmons A, Clines GA, Sartiel A, Gatti RA, Chessa L, Sanal O, Lavin MF, Jaspers NG, Taylor AM, Arlett CF, Miki T, Weissman SM, Lovett M, Collins FS, Shiloh Y. Savitsky K, et al. Among authors: shiloh y. Science. 1995 Jun 23;268(5218):1749-53. doi: 10.1126/science.7792600. Science. 1995. PMID: 7792600
Atm knock-in mice harboring an in-frame deletion corresponding to the human ATM 7636del9 common mutation exhibit a variant phenotype.
Spring K, Cross S, Li C, Watters D, Ben-Senior L, Waring P, Ahangari F, Lu SL, Chen P, Misko I, Paterson C, Kay G, Smorodinsky NI, Shiloh Y, Lavin MF. Spring K, et al. Among authors: shiloh y. Cancer Res. 2001 Jun 1;61(11):4561-8. Cancer Res. 2001. PMID: 11389091
ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks.
Li N, Banin S, Ouyang H, Li GC, Courtois G, Shiloh Y, Karin M, Rotman G. Li N, et al. Among authors: shiloh y. J Biol Chem. 2001 Mar 23;276(12):8898-903. doi: 10.1074/jbc.M009809200. Epub 2000 Dec 12. J Biol Chem. 2001. PMID: 11114307
The genetic defect in ataxia-telangiectasia.
Lavin MF, Shiloh Y. Lavin MF, et al. Among authors: shiloh y. Annu Rev Immunol. 1997;15:177-202. doi: 10.1146/annurev.immunol.15.1.177. Annu Rev Immunol. 1997. PMID: 9143686 Review.
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