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Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities.
Koyanagi S, Tanigawa N, Nakagawa H, Soeda S, Shimeno H. Koyanagi S, et al. Among authors: shimeno h. Biochem Pharmacol. 2003 Jan 15;65(2):173-9. doi: 10.1016/s0006-2952(02)01478-8. Biochem Pharmacol. 2003. PMID: 12504793
[Synthesis of sphingomyelin analogues as a sphingomyelinase inhibitor and the application as a blocking agent of extracellular stress signaling].
Tsuji Y, Soeda S, Ochiai T, Mishima K, Iwasaki K, Fujiwara M, Yokomatsu T, Murano T, Akiyama T, Shibuya S, Shimeno H. Tsuji Y, et al. Among authors: shimeno h. Nihon Yakurigaku Zasshi. 2002 Nov;120(1):67P-69P. Nihon Yakurigaku Zasshi. 2002. PMID: 12491783 Japanese.
Effects of experimental diabetes on hepatic drug metabolism in rats: the activities of flavin-containing monooxygenase, the phase II conjugation reactions and glutathione related enzymes.
Toda A, Eyanagi R, Saito H, Soeda S, Shimeno H, Moriyama M, Shigematsu H. Toda A, et al. Among authors: shimeno h. Res Commun Mol Pathol Pharmacol. 2005;117-118:13-27. Res Commun Mol Pathol Pharmacol. 2005. PMID: 18426076
Molecular mechanism for neuro-protective effect of prosaposin against oxidative stress: its regulation of dimeric transcription factor formation.
Ochiai T, Takenaka Y, Kuramoto Y, Kasuya M, Fukuda K, Kimura M, Shimeno H, Misasi R, Hiraiwa M, Soeda S. Ochiai T, et al. Among authors: shimeno h. Biochim Biophys Acta. 2008 Dec;1780(12):1441-7. doi: 10.1016/j.bbagen.2008.07.010. Epub 2008 Jul 28. Biochim Biophys Acta. 2008. PMID: 18706485
Anti-apoptotic roles of plasminogen activator inhibitor-1 as a neurotrophic factor in the central nervous system.
Soeda S, Koyanagi S, Kuramoto Y, Kimura M, Oda M, Kozako T, Hayashida S, Shimeno H. Soeda S, et al. Among authors: shimeno h. Thromb Haemost. 2008 Dec;100(6):1014-20. doi: 10.1160/th08-04-0259. Thromb Haemost. 2008. PMID: 19132224 Review.
Vasohibin induces prolyl hydroxylase-mediated degradation of hypoxia-inducible factor-1α in human umbilical vein endothelial cells.
Kozako T, Matsumoto N, Kuramoto Y, Sakata A, Motonagare R, Aikawa A, Imoto M, Toda A, Honda S, Shimeno H, Soeda S. Kozako T, et al. Among authors: shimeno h. FEBS Lett. 2012 Apr 5;586(7):1067-72. doi: 10.1016/j.febslet.2012.03.007. Epub 2012 Mar 13. FEBS Lett. 2012. PMID: 22569265 Free article.
Modulation of circadian rhythm of DNA synthesis in tumor cells by inhibiting platelet-derived growth factor signaling.
Nakagawa H, Koyanagi S, Kuramoto Y, Yoshizumi A, Matsunaga N, Shimeno H, Soeda S, Ohdo S. Nakagawa H, et al. Among authors: shimeno h. J Pharmacol Sci. 2008 Aug;107(4):401-7. doi: 10.1254/jphs.08080fp. Epub 2008 Aug 5. J Pharmacol Sci. 2008. PMID: 18678981
Inhibition of lipopolysaccharide-induced release of interleukin-8 from intestinal epithelial cells by SMA, a novel inhibitor of sphingomyelinase and its therapeutic effect on dextran sulphate sodium-induced colitis in mice.
Sakata A, Yasuda K, Ochiai T, Shimeno H, Hikishima S, Yokomatsu T, Shibuya S, Soeda S. Sakata A, et al. Among authors: shimeno h. Cell Immunol. 2007 Jan;245(1):24-31. doi: 10.1016/j.cellimm.2007.03.005. Epub 2007 Apr 27. Cell Immunol. 2007. PMID: 17466962
Acid sphingomyelinase inhibition suppresses lipopolysaccharide-mediated release of inflammatory cytokines from macrophages and protects against disease pathology in dextran sulphate sodium-induced colitis in mice.
Sakata A, Ochiai T, Shimeno H, Hikishima S, Yokomatsu T, Shibuya S, Toda A, Eyanagi R, Soeda S. Sakata A, et al. Among authors: shimeno h. Immunology. 2007 Sep;122(1):54-64. doi: 10.1111/j.1365-2567.2007.02612.x. Epub 2007 Apr 23. Immunology. 2007. PMID: 17451462 Free PMC article.
Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo.
Ochiai T, Shimeno H, Mishima K, Iwasaki K, Fujiwara M, Tanaka H, Shoyama Y, Toda A, Eyanagi R, Soeda S. Ochiai T, et al. Among authors: shimeno h. Biochim Biophys Acta. 2007 Apr;1770(4):578-84. doi: 10.1016/j.bbagen.2006.11.012. Epub 2006 Dec 5. Biochim Biophys Acta. 2007. PMID: 17215084
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