Shimizu A - Search Results

1

Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype.

Bielenberg DR, Hida Y, Shimizu A, Kaipainen A, Kreuter M, Kim CC, Klagsbrun M. Bielenberg DR, et al. Among authors: shimizu a. J Clin Invest. 2004 Nov;114(9):1260-71. doi: 10.1172/JCI21378. J Clin Invest. 2004. PMID: 15520858 Free PMC article.

2

Semaphorin-induced cytoskeletal collapse and repulsion of endothelial cells.

Bielenberg DR, Shimizu A, Klagsbrun M. Bielenberg DR, et al. Among authors: shimizu a. Methods Enzymol. 2008;443:299-314. doi: 10.1016/S0076-6879(08)02015-6. Methods Enzymol. 2008. PMID: 18772022

3

Semaphorin 3E, an exception to the rule.

Klagsbrun M, Shimizu A. Klagsbrun M, et al. Among authors: shimizu a. J Clin Invest. 2010 Aug;120(8):2658-60. doi: 10.1172/JCI44110. Epub 2010 Jul 26. J Clin Invest. 2010. PMID: 20664165 Free PMC article.

4

Hypoxia induces tumor and endothelial cell migration in a semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor neuropilin 2.

Coma S, Shimizu A, Klagsbrun M. Coma S, et al. Among authors: shimizu a. Cell Adh Migr. 2011 May-Jun;5(3):266-75. doi: 10.4161/cam.5.3.16294. Epub 2011 May 1. Cell Adh Migr. 2011. PMID: 21610314 Free PMC article.

5

Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas.

Shahrabi-Farahani S, Wang L, Zwaans BM, Santana JM, Shimizu A, Takashima S, Kreuter M, Coultas L, D'Amore PA, Arbeit JM, Akslen LA, Bielenberg DR. Shahrabi-Farahani S, et al. Among authors: shimizu a. Lab Invest. 2014 Jul;94(7):752-65. doi: 10.1038/labinvest.2014.66. Epub 2014 May 5. Lab Invest. 2014. PMID: 24791743 Free PMC article.

6

Site-directed mutagenesis in the B-neuropilin-2 domain selectively enhances its affinity to VEGF165, but not to semaphorin 3F.

Geretti E, Shimizu A, Kurschat P, Klagsbrun M. Geretti E, et al. Among authors: shimizu a. J Biol Chem. 2007 Aug 31;282(35):25698-707. doi: 10.1074/jbc.M702942200. Epub 2007 Jun 26. J Biol Chem. 2007. PMID: 17595163 Free article.

7

Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis.

Geretti E, Shimizu A, Klagsbrun M. Geretti E, et al. Among authors: shimizu a. Angiogenesis. 2008;11(1):31-9. doi: 10.1007/s10456-008-9097-1. Epub 2008 Feb 19. Angiogenesis. 2008. PMID: 18283547 Review.

8

Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F.

Coma S, Amin DN, Shimizu A, Lasorella A, Iavarone A, Klagsbrun M. Coma S, et al. Among authors: shimizu a. Cancer Res. 2010 May 1;70(9):3823-32. doi: 10.1158/0008-5472.CAN-09-3048. Epub 2010 Apr 13. Cancer Res. 2010. PMID: 20388805 Free PMC article.

9

A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression.

Geretti E, van Meeteren LA, Shimizu A, Dudley AC, Claesson-Welsh L, Klagsbrun M. Geretti E, et al. Among authors: shimizu a. Mol Cancer Res. 2010 Aug;8(8):1063-73. doi: 10.1158/1541-7786.MCR-10-0157. Epub 2010 Jul 22. Mol Cancer Res. 2010. PMID: 20651020 Free PMC article.

10

Merlin/NF2 regulates angiogenesis in schwannomas through a Rac1/semaphorin 3F-dependent mechanism.

Wong HK, Shimizu A, Kirkpatrick ND, Garkavtsev I, Chan AW, di Tomaso E, Klagsbrun M, Jain RK. Wong HK, et al. Among authors: shimizu a. Neoplasia. 2012 Feb;14(2):84-94. doi: 10.1593/neo.111600. Neoplasia. 2012. PMID: 22431917 Free PMC article.

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