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Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug.
Pharmacol Res. 2018 Oct;136:140-150. doi: 10.1016/j.phrs.2018.09.007. Epub 2018 Sep 13.
Pharmacol Res. 2018.
PMID: 30219580
Free PMC article.
Clinical Trial.
Vamorolone trial in Duchenne muscular dystrophy shows dose-related improvement of muscle function.
Hoffman EP, Schwartz BD, Mengle-Gaw LJ, Smith EC, Castro D, Mah JK, McDonald CM, Kuntz NL, Finkel RS, Guglieri M, Bushby K, Tulinius M, Nevo Y, Ryan MM, Webster R, Smith AL, Morgenroth LP, Arrieta A, Shimony M, Siener C, Jaros M, Shale P, McCall JM, Nagaraju K, van den Anker J, Conklin LS, Cnaan A, Gordish-Dressman H, Damsker JM, Clemens PR; Cooperative International Neuromuscular Research Group.
Hoffman EP, et al. Among authors: shimony m.
Neurology. 2019 Sep 24;93(13):e1312-e1323. doi: 10.1212/WNL.0000000000008168. Epub 2019 Aug 26.
Neurology. 2019.
PMID: 31451516
Free PMC article.
Clinical Trial.
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Efficacy and safety of vamorolone in Duchenne muscular dystrophy: An 18-month interim analysis of a non-randomized open-label extension study.
Smith EC, Conklin LS, Hoffman EP, Clemens PR, Mah JK, Finkel RS, Guglieri M, Tulinius M, Nevo Y, Ryan MM, Webster R, Castro D, Kuntz NL, Kerchner L, Morgenroth LP, Arrieta A, Shimony M, Jaros M, Shale P, Gordish-Dressman H, Hagerty L, Dang UJ, Damsker JM, Schwartz BD, Mengle-Gaw LJ, McDonald CM; CINRG VBP15 and DNHS Investigators.
Smith EC, et al. Among authors: shimony m.
PLoS Med. 2020 Sep 21;17(9):e1003222. doi: 10.1371/journal.pmed.1003222. eCollection 2020 Sep.
PLoS Med. 2020.
PMID: 32956407
Free PMC article.
Clinical Trial.
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Sodium bicarbonate administration and outcome in preterm infants.
Berg CS, Barnette AR, Myers BJ, Shimony MK, Barton AW, Inder TE.
Berg CS, et al. Among authors: shimony mk.
J Pediatr. 2010 Oct;157(4):684-7. doi: 10.1016/j.jpeds.2010.05.019. Epub 2010 Jun 30.
J Pediatr. 2010.
PMID: 20580021
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The relationship between sugar-sweetened beverages and liver enzymes among healthy premenopausal women: a prospective cohort study.
Shimony MK, Schliep KC, Schisterman EF, Ahrens KA, Sjaarda LA, Rotman Y, Perkins NJ, Pollack AZ, Wactawski-Wende J, Mumford SL.
Shimony MK, et al.
Eur J Nutr. 2016 Mar;55(2):569-576. doi: 10.1007/s00394-015-0876-3. Epub 2015 Mar 24.
Eur J Nutr. 2016.
PMID: 25801628
Free PMC article.
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