Shinohara M - Search Results

1

Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease.

Shinohara M, Murray ME, Frank RD, Shinohara M, DeTure M, Yamazaki Y, Tachibana M, Atagi Y, Davis MD, Liu CC, Zhao N, Painter MM, Petersen RC, Fryer JD, Crook JE, Dickson DW, Bu G, Kanekiyo T. Shinohara M, et al. Acta Neuropathol. 2016 Aug;132(2):225-234. doi: 10.1007/s00401-016-1580-y. Epub 2016 May 14. Acta Neuropathol. 2016. PMID: 27179972 Free PMC article.

2

Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms.

Li J, Kanekiyo T, Shinohara M, Zhang Y, LaDu MJ, Xu H, Bu G. Li J, et al. Among authors: shinohara m. J Biol Chem. 2012 Dec 28;287(53):44593-601. doi: 10.1074/jbc.M112.420224. Epub 2012 Nov 6. J Biol Chem. 2012. PMID: 23132858 Free PMC article.

3

LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.

Kanekiyo T, Liu CC, Shinohara M, Li J, Bu G. Kanekiyo T, et al. Among authors: shinohara m. J Neurosci. 2012 Nov 14;32(46):16458-65. doi: 10.1523/JNEUROSCI.3987-12.2012. J Neurosci. 2012. PMID: 23152628 Free PMC article.

4

Brain regional correlation of amyloid-β with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-β accumulation.

Shinohara M, Petersen RC, Dickson DW, Bu G. Shinohara M, et al. Acta Neuropathol. 2013 Apr;125(4):535-47. doi: 10.1007/s00401-013-1086-9. Epub 2013 Jan 31. Acta Neuropathol. 2013. PMID: 23371365 Free PMC article.

5

Neuronal clearance of amyloid-β by endocytic receptor LRP1.

Kanekiyo T, Cirrito JR, Liu CC, Shinohara M, Li J, Schuler DR, Shinohara M, Holtzman DM, Bu G. Kanekiyo T, et al. Among authors: shinohara m. J Neurosci. 2013 Dec 4;33(49):19276-83. doi: 10.1523/JNEUROSCI.3487-13.2013. J Neurosci. 2013. PMID: 24305823 Free PMC article.

6

Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.

Zhao J, Fu Y, Liu CC, Shinohara M, Nielsen HM, Dong Q, Kanekiyo T, Bu G. Zhao J, et al. Among authors: shinohara m. J Biol Chem. 2014 Apr 18;289(16):11282-11292. doi: 10.1074/jbc.M113.526095. Epub 2014 Mar 5. J Biol Chem. 2014. PMID: 24599963 Free PMC article.

7

Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer's disease.

Shinohara M, Fujioka S, Murray ME, Wojtas A, Baker M, Rovelet-Lecrux A, Rademakers R, Das P, Parisi JE, Graff-Radford NR, Petersen RC, Dickson DW, Bu G. Shinohara M, et al. Brain. 2014 May;137(Pt 5):1533-49. doi: 10.1093/brain/awu046. Epub 2014 Mar 12. Brain. 2014. PMID: 24625695 Free PMC article.

8

Apolipoprotein E Inhibits Cerebrovascular Pericyte Mobility through a RhoA Protein-mediated Pathway.

Casey CS, Atagi Y, Yamazaki Y, Shinohara M, Tachibana M, Fu Y, Bu G, Kanekiyo T. Casey CS, et al. Among authors: shinohara m. J Biol Chem. 2015 May 29;290(22):14208-17. doi: 10.1074/jbc.M114.625251. Epub 2015 Apr 22. J Biol Chem. 2015. PMID: 25903128 Free PMC article.

9

Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model.

Cook C, Kang SS, Carlomagno Y, Lin WL, Yue M, Kurti A, Shinohara M, Jansen-West K, Perkerson E, Castanedes-Casey M, Rousseau L, Phillips V, Bu G, Dickson DW, Petrucelli L, Fryer JD. Cook C, et al. Among authors: shinohara m. Hum Mol Genet. 2015 Nov 1;24(21):6198-212. doi: 10.1093/hmg/ddv336. Epub 2015 Aug 13. Hum Mol Genet. 2015. PMID: 26276810 Free PMC article.

10

Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1.

Tachibana M, Shinohara M, Yamazaki Y, Liu CC, Rogers J, Bu G, Kanekiyo T. Tachibana M, et al. Among authors: shinohara m. Exp Neurol. 2016 Mar;277:1-9. doi: 10.1016/j.expneurol.2015.12.003. Epub 2015 Dec 11. Exp Neurol. 2016. PMID: 26688581 Free PMC article.

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