Shiraishi A - Search Results

1

Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer's disease: randomized, double-blind, placebo-controlled study.

Timmers M, Streffer JR, Russu A, Tominaga Y, Shimizu H, Shiraishi A, Tatikola K, Smekens P, Börjesson-Hanson A, Andreasen N, Matias-Guiu J, Baquero M, Boada M, Tesseur I, Tritsmans L, Van Nueten L, Engelborghs S. Timmers M, et al. Among authors: shiraishi a. Alzheimers Res Ther. 2018 Aug 23;10(1):85. doi: 10.1186/s13195-018-0415-6. Alzheimers Res Ther. 2018. PMID: 30134967 Free PMC article. Clinical Trial.

2

Efficacy and safety of fixed doses of intranasal Esketamine as an add-on therapy to Oral antidepressants in Japanese patients with treatment-resistant depression: a phase 2b randomized clinical study.

Takahashi N, Yamada A, Shiraishi A, Shimizu H, Goto R, Tominaga Y. Takahashi N, et al. Among authors: shiraishi a. BMC Psychiatry. 2021 Oct 25;21(1):526. doi: 10.1186/s12888-021-03538-y. BMC Psychiatry. 2021. PMID: 34696742 Free PMC article. Clinical Trial.

3

Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA-repair, methyltransferase, had been disrupted by gene targeting.

Tominaga Y, Tsuzuki T, Shiraishi A, Kawate H, Sekiguchi M. Tominaga Y, et al. Among authors: shiraishi a. Carcinogenesis. 1997 May;18(5):889-96. doi: 10.1093/carcin/18.5.889. Carcinogenesis. 1997. PMID: 9163672

4

Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent.

Tsuzuki T, Sakumi K, Shiraishi A, Kawate H, Igarashi H, Iwakuma T, Tominaga Y, Zhang S, Shimizu S, Ishikawa T et AL. Tsuzuki T, et al. Among authors: shiraishi a. Carcinogenesis. 1996 Jun;17(6):1215-20. doi: 10.1093/carcin/17.6.1215. Carcinogenesis. 1996. PMID: 8681434

5

Isolation and characterization of cDNA and genomic sequences for mouse O6-methylguanine-DNA methyltransferase.

Shiraishi A, Sakumi K, Nakatsu Y, Hayakawa H, Sekiguchi M. Shiraishi A, et al. Carcinogenesis. 1992 Feb;13(2):289-96. doi: 10.1093/carcin/13.2.289. Carcinogenesis. 1992. PMID: 1371245

6

Organization and expression of the mouse gene for DNA repair methyltransferase.

Iwakuma T, Shiraishi A, Fukuhara M, Kawate H, Sekiguchi M. Iwakuma T, et al. Among authors: shiraishi a. DNA Cell Biol. 1996 Oct;15(10):863-72. doi: 10.1089/dna.1996.15.863. DNA Cell Biol. 1996. PMID: 8892758

7

Methylnitrosourea-induced tumorigenesis in MGMT gene knockout mice.

Sakumi K, Shiraishi A, Shimizu S, Tsuzuki T, Ishikawa T, Sekiguchi M. Sakumi K, et al. Among authors: shiraishi a. Cancer Res. 1997 Jun 15;57(12):2415-8. Cancer Res. 1997. PMID: 9192819

8

High incidence of nitrosamine-induced tumorigenesis in mice lacking DNA repair methyltransferase.

Iwakuma T, Sakumi K, Nakatsuru Y, Kawate H, Igarashi H, Shiraishi A, Tsuzuki T, Ishikawa T, Sekiguchi M. Iwakuma T, et al. Among authors: shiraishi a. Carcinogenesis. 1997 Aug;18(8):1631-5. doi: 10.1093/carcin/18.8.1631. Carcinogenesis. 1997. PMID: 9276640

9

Increased susceptibility to chemotherapeutic alkylating agents of mice deficient in DNA repair methyltransferase.

Shiraishi A, Sakumi K, Sekiguchi M. Shiraishi A, et al. Carcinogenesis. 2000 Oct;21(10):1879-83. doi: 10.1093/carcin/21.10.1879. Carcinogenesis. 2000. PMID: 11023546

10

Cloning and expresion of cDNA for rat O6-methylguanine-DNA methyltransferase.

Sakumi K, Shiraishi A, Hayakawa H, Sekiguchi M. Sakumi K, et al. Among authors: shiraishi a. Nucleic Acids Res. 1991 Oct 25;19(20):5597-601. doi: 10.1093/nar/19.20.5597. Nucleic Acids Res. 1991. PMID: 1945835 Free PMC article.

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