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Identification and validation of DOCK4 as a potential biomarker for risk of bone metastasis development in patients with early breast cancer.
Westbrook JA, Wood SL, Cairns DA, McMahon K, Gahlaut R, Thygesen H, Shires M, Roberts S, Marshall H, Oliva MR, Dunning MJ, Hanby AM, Selby PJ, Speirs V, Mavria G, Coleman RE, Brown JE. Westbrook JA, et al. Among authors: shires m. J Pathol. 2019 Mar;247(3):381-391. doi: 10.1002/path.5197. Epub 2019 Jan 25. J Pathol. 2019. PMID: 30426503 Free PMC article.
Mutations in MEGF10, a regulator of satellite cell myogenesis, cause early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD).
Logan CV, Lucke B, Pottinger C, Abdelhamed ZA, Parry DA, Szymanska K, Diggle CP, van Riesen A, Morgan JE, Markham G, Ellis I, Manzur AY, Markham AF, Shires M, Helliwell T, Scoto M, Hübner C, Bonthron DT, Taylor GR, Sheridan E, Muntoni F, Carr IM, Schuelke M, Johnson CA. Logan CV, et al. Among authors: shires m. Nat Genet. 2011 Nov 20;43(12):1189-92. doi: 10.1038/ng.995. Nat Genet. 2011. PMID: 22101682
Toward routine use of 3D histopathology as a research tool.
Roberts N, Magee D, Song Y, Brabazon K, Shires M, Crellin D, Orsi NM, Quirke R, Quirke P, Treanor D. Roberts N, et al. Among authors: shires m. Am J Pathol. 2012 May;180(5):1835-42. doi: 10.1016/j.ajpath.2012.01.033. Epub 2012 Apr 9. Am J Pathol. 2012. PMID: 22490922 Free PMC article.
Artificial Intelligence-Assisted Amphiregulin and Epiregulin IHC Predicts Panitumumab Benefit in RAS Wild-Type Metastatic Colorectal Cancer.
Williams CJM, Seligmann JF, Elliott F, Shires M, Richman SD, Brown S, Zhang L, Singh S, Pugh J, Xu XM, Muranyi A, Guetter C, Lorsakul A, Kurkure U, Zhao Z, Martin J, Wang X, Nguyen K, Liu WW, Yan D, West NP, Barrett JH, Barnes M, Bai I, Seymour MT, Quirke P, Shanmugam K. Williams CJM, et al. Among authors: shires m. Clin Cancer Res. 2021 Jun 15;27(12):3422-3431. doi: 10.1158/1078-0432.CCR-21-0120. Epub 2021 Apr 22. Clin Cancer Res. 2021. PMID: 33888518
Homozygous mutations in PXDN cause congenital cataract, corneal opacity, and developmental glaucoma.
Khan K, Rudkin A, Parry DA, Burdon KP, McKibbin M, Logan CV, Abdelhamed ZI, Muecke JS, Fernandez-Fuentes N, Laurie KJ, Shires M, Fogarty R, Carr IM, Poulter JA, Morgan JE, Mohamed MD, Jafri H, Raashid Y, Meng N, Piseth H, Toomes C, Casson RJ, Taylor GR, Hammerton M, Sheridan E, Johnson CA, Inglehearn CF, Craig JE, Ali M. Khan K, et al. Among authors: shires m. Am J Hum Genet. 2011 Sep 9;89(3):464-73. doi: 10.1016/j.ajhg.2011.08.005. Am J Hum Genet. 2011. PMID: 21907015 Free PMC article.
Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer: implications for tumour immune evasion.
Hornigold N, Dunn KR, Craven RA, Zougman A, Trainor S, Shreeve R, Brown J, Sewell H, Shires M, Knowles M, Fukuwatari T, Maher ER, Burns J, Bhattarai S, Menon M, Brazma A, Scelo G, Feulner L, Riazalhosseini Y, Lathrop M, Harris A, Selby PJ, Banks RE, Vasudev NS. Hornigold N, et al. Among authors: shires m. Br J Cancer. 2020 Jul;123(1):137-147. doi: 10.1038/s41416-020-0874-y. Epub 2020 May 11. Br J Cancer. 2020. PMID: 32390008 Free PMC article.
63 results