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Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats.
J Pharmacol Exp Ther. 2008 Dec;327(3):941-53. doi: 10.1124/jpet.108.140350. Epub 2008 Sep 4.
J Pharmacol Exp Ther. 2008.
PMID: 18772318
Free PMC article.
An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission.
Shirey JK, Xiang Z, Orton D, Brady AE, Johnson KA, Williams R, Ayala JE, Rodriguez AL, Wess J, Weaver D, Niswender CM, Conn PJ.
Shirey JK, et al.
Nat Chem Biol. 2008 Jan;4(1):42-50. doi: 10.1038/nchembio.2007.55. Epub 2007 Dec 2.
Nat Chem Biol. 2008.
PMID: 18059262
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Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity.
Marlo JE, Niswender CM, Days EL, Bridges TM, Xiang Y, Rodriguez AL, Shirey JK, Brady AE, Nalywajko T, Luo Q, Austin CA, Williams MB, Kim K, Williams R, Orton D, Brown HA, Lindsley CW, Weaver CD, Conn PJ.
Marlo JE, et al. Among authors: shirey jk.
Mol Pharmacol. 2009 Mar;75(3):577-88. doi: 10.1124/mol.108.052886. Epub 2008 Dec 1.
Mol Pharmacol. 2009.
PMID: 19047481
Free PMC article.
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Synthesis and structure-activity relationships of allosteric potentiators of the m(4) muscarinic acetylcholine receptor.
Kennedy JP, Bridges TM, Gentry PR, Brogan JT, Kane AS, Jones CK, Brady AE, Shirey JK, Conn PJ, Lindsley CW.
Kennedy JP, et al. Among authors: shirey jk.
ChemMedChem. 2009 Oct;4(10):1600-7. doi: 10.1002/cmdc.200900231.
ChemMedChem. 2009.
PMID: 19705385
Free PMC article.
No abstract available.
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A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning.
Shirey JK, Brady AE, Jones PJ, Davis AA, Bridges TM, Kennedy JP, Jadhav SB, Menon UN, Xiang Z, Watson ML, Christian EP, Doherty JJ, Quirk MC, Snyder DH, Lah JJ, Levey AI, Nicolle MM, Lindsley CW, Conn PJ.
Shirey JK, et al.
J Neurosci. 2009 Nov 11;29(45):14271-86. doi: 10.1523/JNEUROSCI.3930-09.2009.
J Neurosci. 2009.
PMID: 19906975
Free PMC article.
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Allosteric activators of muscarinic receptors as novel approaches for treatment of CNS disorders.
Digby GJ, Shirey JK, Conn PJ.
Digby GJ, et al. Among authors: shirey jk.
Mol Biosyst. 2010 Aug;6(8):1345-54. doi: 10.1039/c002938f. Epub 2010 Jun 25.
Mol Biosyst. 2010.
PMID: 20582339
Free PMC article.
Review.
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Massive fatal hemoptysis secondary to invasive aspergillosis in a patient with COPD.
Pittokopitis K, Herriott DT, Shirey JK.
Pittokopitis K, et al. Among authors: shirey jk.
Chest. 1983 Mar;83(3):583. doi: 10.1378/chest.83.3.583a.
Chest. 1983.
PMID: 6825497
No abstract available.
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HEPARIN IN THE TREATMENT OF CHRONIC OBSTRUCTIVE BRONCHOPULMONARY DISEASE.
BOYLE JP, SMART RH, SHIREY JK.
BOYLE JP, et al. Among authors: shirey jk.
Am J Cardiol. 1964 Jul;14:25-8. doi: 10.1016/0002-9149(64)90100-6.
Am J Cardiol. 1964.
PMID: 14176885
No abstract available.
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