Shizu R - Search Results

1

Functional Interaction between Pregnane X Receptor and Yes-Associated Protein in Xenobiotic-Dependent Liver Hypertrophy and Drug Metabolism.

Abe T, Shizu R, Sasaki T, Shimizu Y, Hosaka T, Kodama S, Matsuzawa A, Yoshinari K. Abe T, et al. Among authors: shizu r. J Pharmacol Exp Ther. 2019 Dec;371(3):590-601. doi: 10.1124/jpet.119.258632. Epub 2019 Sep 18. J Pharmacol Exp Ther. 2019. PMID: 31533970

2

MicroRNA-122 down-regulation is involved in phenobarbital-mediated activation of the constitutive androstane receptor.

Shizu R, Shindo S, Yoshida T, Numazawa S. Shizu R, et al. PLoS One. 2012;7(7):e41291. doi: 10.1371/journal.pone.0041291. Epub 2012 Jul 18. PLoS One. 2012. PMID: 22815988 Free PMC article.

3

Interaction of the phosphorylated DNA-binding domain in nuclear receptor CAR with its ligand-binding domain regulates CAR activation.

Shizu R, Min J, Sobhany M, Pedersen LC, Mutoh S, Negishi M. Shizu R, et al. J Biol Chem. 2018 Jan 5;293(1):333-344. doi: 10.1074/jbc.M117.806604. Epub 2017 Nov 13. J Biol Chem. 2018. PMID: 29133527 Free PMC article.

4

Cross-talk between constitutive androstane receptor and hypoxia-inducible factor in the regulation of gene expression.

Shizu R, Shindo S, Yoshida T, Numazawa S. Shizu R, et al. Toxicol Lett. 2013 May 23;219(2):143-50. doi: 10.1016/j.toxlet.2013.03.014. Epub 2013 Mar 23. Toxicol Lett. 2013. PMID: 23528251

5

Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation.

Shizu R, Osabe M, Perera L, Moore R, Sueyoshi T, Negishi M. Shizu R, et al. Mol Cell Biol. 2017 May 2;37(10):e00649-16. doi: 10.1128/MCB.00649-16. Print 2017 May 15. Mol Cell Biol. 2017. PMID: 28265001 Free PMC article.

6

[Involvement of microRNA in the induction of drug-metabolizing enzymes].

Shizu R, Numazawa S, Yoshida T. Shizu R, et al. Yakugaku Zasshi. 2012;132(3):311-8. doi: 10.1248/yakushi.132.311. Yakugaku Zasshi. 2012. PMID: 22382835 Review. Japanese.

7

Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.

Shizu R, Benoki S, Numakura Y, Kodama S, Miyata M, Yamazoe Y, Yoshinari K. Shizu R, et al. PLoS One. 2013 Apr 23;8(4):e61802. doi: 10.1371/journal.pone.0061802. Print 2013. PLoS One. 2013. PMID: 23626729 Free PMC article.

8

PXR stimulates growth factor-mediated hepatocyte proliferation by cross-talk with the FOXO transcription factor.

Shizu R, Abe T, Benoki S, Takahashi M, Kodama S, Miayata M, Matsuzawa A, Yoshinari K. Shizu R, et al. Biochem J. 2016 Feb 1;473(3):257-66. doi: 10.1042/BJ20150734. Epub 2015 Nov 16. Biochem J. 2016. PMID: 26574435

9

Role of YAP Activation in Nuclear Receptor CAR-Mediated Proliferation of Mouse Hepatocytes.

Abe T, Amaike Y, Shizu R, Takahashi M, Kano M, Hosaka T, Sasaki T, Kodama S, Matsuzawa A, Yoshinari K. Abe T, et al. Among authors: shizu r. Toxicol Sci. 2018 Oct 1;165(2):408-419. doi: 10.1093/toxsci/kfy149. Toxicol Sci. 2018. PMID: 29893953

10

Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR.

Yoshimaru S, Shizu R, Tsuruta S, Amaike Y, Kano M, Hosaka T, Sasaki T, Yoshinari K. Yoshimaru S, et al. Among authors: shizu r. J Toxicol Sci. 2018;43(7):443-450. doi: 10.2131/jts.43.443. J Toxicol Sci. 2018. PMID: 29973476

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