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Graft-versus-host disease.
Shlomchik WD. Shlomchik WD. Nat Rev Immunol. 2007 May;7(5):340-52. doi: 10.1038/nri2000. Nat Rev Immunol. 2007. PMID: 17438575 Review.
Engineering human peripheral blood stem cell grafts that are depleted of naïve T cells and retain functional pathogen-specific memory T cells.
Bleakley M, Heimfeld S, Jones LA, Turtle C, Krause D, Riddell SR, Shlomchik W. Bleakley M, et al. Biol Blood Marrow Transplant. 2014 May;20(5):705-16. doi: 10.1016/j.bbmt.2014.01.032. Epub 2014 Feb 11. Biol Blood Marrow Transplant. 2014. PMID: 24525279 Free PMC article.
GVL against murine chronic phase and blast phase CML.
Shlomchik W. Shlomchik W. Biol Blood Marrow Transplant. 2008 Jan;14(1 Suppl 1):4. doi: 10.1016/j.bbmt.2007.10.005. Biol Blood Marrow Transplant. 2008. PMID: 18162213 No abstract available.
NCI first International Workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on the biological considerations of hematological relapse following allogeneic stem cell transplantation unrelated to graft-versus-tumor effects: state of the science.
Cairo MS, Jordan CT, Maley CC, Chao C, Melnick A, Armstrong SA, Shlomchik W, Molldrem J, Ferrone S, Mackall C, Zitvogel L, Bishop MR, Giralt SA, June CH. Cairo MS, et al. Biol Blood Marrow Transplant. 2010 Jun;16(6):709-28. doi: 10.1016/j.bbmt.2010.03.002. Epub 2010 Mar 12. Biol Blood Marrow Transplant. 2010. PMID: 20227509 Free PMC article.
Long-term follow-up of a single institution pilot study of sirolimus, tacrolimus, and short course methotrexate for graft versus host disease prophylaxis in mismatched unrelated donor allogeneic stem cell transplantation.
Kim TK, DeVeaux M, Stahl M, Perreault S, Isufi I, Cooper D, Foss F, Shlomchik W, Zelterman D, Zeidan AM, Seropian S. Kim TK, et al. Ann Hematol. 2019 Jan;98(1):237-240. doi: 10.1007/s00277-018-3427-1. Epub 2018 Jul 19. Ann Hematol. 2019. PMID: 30027436 Clinical Trial. No abstract available.
Graft-infiltrating host dendritic cells play a key role in organ transplant rejection.
Zhuang Q, Liu Q, Divito SJ, Zeng Q, Yatim KM, Hughes AD, Rojas-Canales DM, Nakao A, Shufesky WJ, Williams AL, Humar R, Hoffman RA, Shlomchik WD, Oberbarnscheidt MH, Lakkis FG, Morelli AE. Zhuang Q, et al. Among authors: shlomchik wd. Nat Commun. 2016 Aug 24;7:12623. doi: 10.1038/ncomms12623. Nat Commun. 2016. PMID: 27554168 Free PMC article.
APCs in the liver and spleen recruit activated allogeneic CD8+ T cells to elicit hepatic graft-versus-host disease.
Zhang Y, Shlomchik WD, Joe G, Louboutin JP, Zhu J, Rivera A, Giannola D, Emerson SG. Zhang Y, et al. Among authors: shlomchik wd. J Immunol. 2002 Dec 15;169(12):7111-8. doi: 10.4049/jimmunol.169.12.7111. J Immunol. 2002. PMID: 12471148
In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease.
Morin-Zorman S, Wysocki C, Zhu J, Li H, Zorman S, Matte-Martone C, Kisanga E, McNiff J, Jain D, Gonzalez D, Rothstein DM, Lakkis FG, Haberman A, Shlomchik WD. Morin-Zorman S, et al. Among authors: shlomchik wd. Blood Adv. 2019 Jul 23;3(14):2082-2092. doi: 10.1182/bloodadvances.2019000227. Blood Adv. 2019. PMID: 31296496 Free PMC article.
Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β.
Mohammed J, Beura LK, Bobr A, Astry B, Chicoine B, Kashem SW, Welty NE, Igyártó BZ, Wijeyesinghe S, Thompson EA, Matte C, Bartholin L, Kaplan A, Sheppard D, Bridges AG, Shlomchik WD, Masopust D, Kaplan DH. Mohammed J, et al. Among authors: shlomchik wd. Nat Immunol. 2016 Apr;17(4):414-21. doi: 10.1038/ni.3396. Epub 2016 Feb 22. Nat Immunol. 2016. PMID: 26901152 Free PMC article.
Langerhans cells are not required for efficient skin graft rejection.
Obhrai JS, Oberbarnscheidt M, Zhang N, Mueller DL, Shlomchik WD, Lakkis FG, Shlomchik MJ, Kaplan DH. Obhrai JS, et al. Among authors: shlomchik wd, shlomchik mj. J Invest Dermatol. 2008 Aug;128(8):1950-5. doi: 10.1038/jid.2008.52. Epub 2008 Mar 13. J Invest Dermatol. 2008. PMID: 18337832 Free PMC article.
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