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Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2.
Eck MJ, Pluskey S, TrĂ¼b T, Harrison SC, Shoelson SE. Eck MJ, et al. Among authors: shoelson se. Nature. 1996 Jan 18;379(6562):277-80. doi: 10.1038/379277a0. Nature. 1996. PMID: 8538796
IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85.
Myers MG Jr, Backer JM, Sun XJ, Shoelson S, Hu P, Schlessinger J, Yoakim M, Schaffhausen B, White MF. Myers MG Jr, et al. Among authors: shoelson s. Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10350-4. doi: 10.1073/pnas.89.21.10350. Proc Natl Acad Sci U S A. 1992. PMID: 1332046 Free PMC article.
Physical and functional interactions between SH2 and SH3 domains of the Src family protein tyrosine kinase p59fyn.
Panchamoorthy G, Fukazawa T, Stolz L, Payne G, Reedquist K, Shoelson S, Songyang Z, Cantley L, Walsh C, Band H. Panchamoorthy G, et al. Among authors: shoelson s. Mol Cell Biol. 1994 Sep;14(9):6372-85. doi: 10.1128/mcb.14.9.6372. Mol Cell Biol. 1994. PMID: 7520528 Free PMC article.
p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase.
Panchamoorthy G, Fukazawa T, Miyake S, Soltoff S, Reedquist K, Druker B, Shoelson S, Cantley L, Band H. Panchamoorthy G, et al. Among authors: shoelson s. J Biol Chem. 1996 Feb 9;271(6):3187-94. doi: 10.1074/jbc.271.6.3187. J Biol Chem. 1996. PMID: 8621719
A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.
van der Geer P, Wiley S, Lai VK, Olivier JP, Gish GD, Stephens R, Kaplan D, Shoelson S, Pawson T. van der Geer P, et al. Among authors: shoelson s. Curr Biol. 1995 Apr 1;5(4):404-12. doi: 10.1016/s0960-9822(95)00081-9. Curr Biol. 1995. PMID: 7542991
Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit.
Carpenter CL, Auger KR, Chanudhuri M, Yoakim M, Schaffhausen B, Shoelson S, Cantley LC. Carpenter CL, et al. Among authors: shoelson s. J Biol Chem. 1993 May 5;268(13):9478-83. J Biol Chem. 1993. PMID: 7683653
Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5.
Cai D, Dhe-Paganon S, Melendez PA, Lee J, Shoelson SE. Cai D, et al. Among authors: shoelson se. J Biol Chem. 2003 Jul 11;278(28):25323-30. doi: 10.1074/jbc.M212430200. Epub 2003 May 1. J Biol Chem. 2003. PMID: 12730241
Crystal structures of human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating protein (RabGAP) domains reveal critical elements for GLUT4 translocation.
Park SY, Jin W, Woo JR, Shoelson SE. Park SY, et al. Among authors: shoelson se. J Biol Chem. 2011 May 20;286(20):18130-8. doi: 10.1074/jbc.M110.217323. Epub 2011 Mar 23. J Biol Chem. 2011. PMID: 21454505 Free PMC article.
Kinase activation through dimerization by human SH2-B.
Nishi M, Werner ED, Oh BC, Frantz JD, Dhe-Paganon S, Hansen L, Lee J, Shoelson SE. Nishi M, et al. Among authors: shoelson se. Mol Cell Biol. 2005 Apr;25(7):2607-21. doi: 10.1128/MCB.25.7.2607-2621.2005. Mol Cell Biol. 2005. PMID: 15767667 Free PMC article.
A phenylalanine zipper mediates APS dimerization.
Dhe-Paganon S, Werner ED, Nishi M, Hansen L, Chi YI, Shoelson SE. Dhe-Paganon S, et al. Among authors: shoelson se. Nat Struct Mol Biol. 2004 Oct;11(10):968-74. doi: 10.1038/nsmb829. Epub 2004 Sep 19. Nat Struct Mol Biol. 2004. PMID: 15378031
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