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Substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and analogues: synthesis, cytotoxic activity, and study of the mechanism of action.
Andreani A, Granaiola M, Locatelli A, Morigi R, Rambaldi M, Varoli L, Calonghi N, Cappadone C, Farruggia G, Stefanelli C, Masotti L, Nguyen TL, Hamel E, Shoemaker RH. Andreani A, et al. Among authors: shoemaker rh. J Med Chem. 2012 Mar 8;55(5):2078-88. doi: 10.1021/jm2012694. Epub 2012 Feb 15. J Med Chem. 2012. PMID: 22283430 Free PMC article.
Substituted E-3-(3-indolylmethylene)-1,3-dihydroindol-2-ones with antitumor activity. In depth study of the effect on growth of breast cancer cells.
Andreani A, Bellini S, Burnelli S, Granaiola M, Leoni A, Locatelli A, Morigi R, Rambaldi M, Varoli L, Calonghi N, Cappadone C, Zini M, Stefanelli C, Masotti L, Shoemaker RH. Andreani A, et al. Among authors: shoemaker rh. J Med Chem. 2010 Aug 12;53(15):5567-75. doi: 10.1021/jm1007165. J Med Chem. 2010. PMID: 20684599 Free PMC article.
Antitumor activity and COMPARE analysis of bis-indole derivatives.
Andreani A, Burnelli S, Granaiola M, Leoni A, Locatelli A, Morigi R, Rambaldi M, Varoli L, Landi L, Prata C, Dalla Sega FV, Caliceti C, Shoemaker RH. Andreani A, et al. Among authors: shoemaker rh. Bioorg Med Chem. 2010 May 1;18(9):3004-11. doi: 10.1016/j.bmc.2010.03.063. Epub 2010 Mar 28. Bioorg Med Chem. 2010. PMID: 20395150
New antitumor imidazo[2,1-b]thiazole guanylhydrazones and analogues.
Andreani A, Burnelli S, Granaiola M, Leoni A, Locatelli A, Morigi R, Rambaldi M, Varoli L, Calonghi N, Cappadone C, Farruggia G, Zini M, Stefanelli C, Masotti L, Radin NS, Shoemaker RH. Andreani A, et al. Among authors: shoemaker rh. J Med Chem. 2008 Feb 28;51(4):809-16. doi: 10.1021/jm701246g. Epub 2008 Feb 6. J Med Chem. 2008. PMID: 18251494
Antitumor activity of new substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and 3-(5-imidazo[2,1-b]thiadiazolylmethylene)-2-indolinones: selectivity against colon tumor cells and effect on cell cycle-related events.
Andreani A, Burnelli S, Granaiola M, Leoni A, Locatelli A, Morigi R, Rambaldi M, Varoli L, Calonghi N, Cappadone C, Voltattorni M, Zini M, Stefanelli C, Masotti L, Shoemaker RH. Andreani A, et al. Among authors: shoemaker rh. J Med Chem. 2008 Dec 11;51(23):7508-13. doi: 10.1021/jm800827q. J Med Chem. 2008. PMID: 19006285
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