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324 results
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A chemical genetic screen for direct v-Src substrates reveals ordered assembly of a retrograde signaling pathway.
Shah K, Shokat KM. Shah K, et al. Among authors: shokat km. Chem Biol. 2002 Jan;9(1):35-47. doi: 10.1016/s1074-5521(02)00086-8. Chem Biol. 2002. PMID: 11841937
Engineering unnatural nucleotide specificity for Rous sarcoma virus tyrosine kinase to uniquely label its direct substrates.
Shah K, Liu Y, Deirmengian C, Shokat KM. Shah K, et al. Among authors: shokat km. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3565-70. doi: 10.1073/pnas.94.8.3565. Proc Natl Acad Sci U S A. 1997. PMID: 9108016 Free PMC article.
Tyrosine kinases: modular signaling enzymes with tunable specificities.
Shokat KM. Shokat KM. Chem Biol. 1995 Aug;2(8):509-14. doi: 10.1016/1074-5521(95)90183-3. Chem Biol. 1995. PMID: 9383454 Review.
Engineering Src family protein kinases with unnatural nucleotide specificity.
Liu Y, Shah K, Yang F, Witucki L, Shokat KM. Liu Y, et al. Among authors: shokat km. Chem Biol. 1998 Feb;5(2):91-101. doi: 10.1016/s1074-5521(98)90143-0. Chem Biol. 1998. PMID: 9495830
Design of allele-specific inhibitors to probe protein kinase signaling.
Bishop AC, Shah K, Liu Y, Witucki L, Kung C, Shokat KM. Bishop AC, et al. Among authors: shokat km. Curr Biol. 1998 Feb 26;8(5):257-66. doi: 10.1016/s0960-9822(98)70198-8. Curr Biol. 1998. PMID: 9501066
A molecular gate which controls unnatural ATP analogue recognition by the tyrosine kinase v-Src.
Liu Y, Shah K, Yang F, Witucki L, Shokat KM. Liu Y, et al. Among authors: shokat km. Bioorg Med Chem. 1998 Aug;6(8):1219-26. doi: 10.1016/s0968-0896(98)00099-6. Bioorg Med Chem. 1998. PMID: 9784863
Structural basis for selective inhibition of Src family kinases by PP1.
Liu Y, Bishop A, Witucki L, Kraybill B, Shimizu E, Tsien J, Ubersax J, Blethrow J, Morgan DO, Shokat KM. Liu Y, et al. Among authors: shokat km. Chem Biol. 1999 Sep;6(9):671-8. doi: 10.1016/s1074-5521(99)80118-5. Chem Biol. 1999. PMID: 10467133
Entry of B cell receptor into signaling domains is inhibited in tolerant B cells.
Weintraub BC, Jun JE, Bishop AC, Shokat KM, Thomas ML, Goodnow CC. Weintraub BC, et al. Among authors: shokat km. J Exp Med. 2000 Apr 17;191(8):1443-8. doi: 10.1084/jem.191.8.1443. J Exp Med. 2000. PMID: 10770810 Free PMC article.
Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue.
Habelhah H, Shah K, Huang L, Burlingame AL, Shokat KM, Ronai Z. Habelhah H, et al. Among authors: shokat km. J Biol Chem. 2001 May 25;276(21):18090-5. doi: 10.1074/jbc.M011396200. Epub 2001 Mar 19. J Biol Chem. 2001. PMID: 11259409
Chemical genetic approaches for the elucidation of signaling pathways.
Alaimo PJ, Shogren-Knaak MA, Shokat KM. Alaimo PJ, et al. Among authors: shokat km. Curr Opin Chem Biol. 2001 Aug;5(4):360-7. doi: 10.1016/s1367-5931(00)00215-5. Curr Opin Chem Biol. 2001. PMID: 11470597 Review.
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