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The neurotrophin-3 receptor TrkC directly phosphorylates and activates the nucleotide exchange factor Dbs to enhance Schwann cell migration.
Yamauchi J, Chan JR, Miyamoto Y, Tsujimoto G, Shooter EM. Yamauchi J, et al. Among authors: shooter em. Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5198-203. doi: 10.1073/pnas.0501160102. Epub 2005 Mar 9. Proc Natl Acad Sci U S A. 2005. PMID: 15758069 Free PMC article.
NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes.
Chan JR, Watkins TA, Cosgaya JM, Zhang C, Chen L, Reichardt LF, Shooter EM, Barres BA. Chan JR, et al. Among authors: shooter em. Neuron. 2004 Jul 22;43(2):183-91. doi: 10.1016/j.neuron.2004.06.024. Neuron. 2004. PMID: 15260955 Free PMC article.
Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPases.
Yamauchi J, Chan JR, Shooter EM. Yamauchi J, et al. Among authors: shooter em. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8774-9. doi: 10.1073/pnas.0402795101. Epub 2004 May 25. Proc Natl Acad Sci U S A. 2004. PMID: 15161978 Free PMC article.
Neurotrophin 3 activation of TrkC induces Schwann cell migration through the c-Jun N-terminal kinase pathway.
Yamauchi J, Chan JR, Shooter EM. Yamauchi J, et al. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14421-6. doi: 10.1073/pnas.2336152100. Epub 2003 Nov 12. Proc Natl Acad Sci U S A. 2003. PMID: 14614136 Free PMC article.
The neurotrophin receptor p75NTR as a positive modulator of myelination.
Cosgaya JM, Chan JR, Shooter EM. Cosgaya JM, et al. Science. 2002 Nov 8;298(5596):1245-8. doi: 10.1126/science.1076595. Science. 2002. PMID: 12424382
Ras activation of a Rac1 exchange factor, Tiam1, mediates neurotrophin-3-induced Schwann cell migration.
Yamauchi J, Miyamoto Y, Tanoue A, Shooter EM, Chan JR. Yamauchi J, et al. Among authors: shooter em. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14889-94. doi: 10.1073/pnas.0507125102. Epub 2005 Oct 3. Proc Natl Acad Sci U S A. 2005. PMID: 16203995 Free PMC article.
BDNF/NT4-5 receptor TrkB and cadherin participate in cell-cell adhesion.
Zhou H, Welcher AA, Shooter EM. Zhou H, et al. J Neurosci Res. 1997 Aug 1;49(3):281-91. doi: 10.1002/(sici)1097-4547(19970801)49:3<281::aid-jnr3>3.0.co;2-8. J Neurosci Res. 1997. PMID: 9260739
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