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Effect of dietary nitrate on blood pressure, endothelial function, and insulin sensitivity in type 2 diabetes.
Gilchrist M, Winyard PG, Aizawa K, Anning C, Shore A, Benjamin N. Gilchrist M, et al. Among authors: shore a. Free Radic Biol Med. 2013 Jul;60:89-97. doi: 10.1016/j.freeradbiomed.2013.01.024. Epub 2013 Feb 8. Free Radic Biol Med. 2013. PMID: 23395779 Clinical Trial.
Twenty-seven patients, age 67.2±4.9 years (18 male), were recruited for a double-blind, randomized, placebo-controlled crossover trial. Participants were randomized to begin, in either order, a 2-week period of supplementation with 250ml beetroot juice daily (active …
Twenty-seven patients, age 67.2±4.9 years (18 male), were recruited for a double-blind, randomized, placebo-controlled crossover tria …
Unique blood pressure characteristics in mother and offspring after early onset preeclampsia.
Lazdam M, de la Horra A, Diesch J, Kenworthy Y, Davis E, Lewandowski AJ, Szmigielski C, Shore A, Mackillop L, Kharbanda R, Alp N, Redman C, Kelly B, Leeson P. Lazdam M, et al. Among authors: shore a. Hypertension. 2012 Nov;60(5):1338-45. doi: 10.1161/HYPERTENSIONAHA.112.198366. Epub 2012 Oct 8. Hypertension. 2012. PMID: 23045462
One hundred forty women were studied 6 to 13 years either after a pregnancy complicated by preeclampsia (45 women with early onset preeclampsia before 34 weeks gestation and 45 women with late-onset preeclampsia) or after a normotensive pregnancy (50 women). ...Comp …
One hundred forty women were studied 6 to 13 years either after a pregnancy complicated by preeclampsia (45 women with early onset pr …
Inorganic Nitrate: Marker or Mediator of Mortality?
Gilchrist M, Shore A. Gilchrist M, et al. Among authors: shore a. J Am Heart Assoc. 2017 Nov 18;6(11):e007782. doi: 10.1161/JAHA.117.007782. J Am Heart Assoc. 2017. PMID: 29151029 Free PMC article. No abstract available.
Baroreflex sensitivity measured by spectral and sequence analysis in cerebrovascular disease : methodological considerations.
Johnson P, Shore A, Potter J, Panerai R, James M. Johnson P, et al. Among authors: shore a. Clin Auton Res. 2006 Aug;16(4):270-5. doi: 10.1007/s10286-006-0351-6. Epub 2006 Jun 12. Clin Auton Res. 2006. PMID: 16770526
A total of 14 subjects were assessed on 2 separate occasions at least 2 weeks apart, and beat-to-beat blood pressure (BP) and ECG trace were recorded for three 5-minute periods. ...
A total of 14 subjects were assessed on 2 separate occasions at least 2 weeks apart, and beat-to-beat blood pressure (BP) and ECG tra
Ageing modifies the effects of beetroot juice supplementation on 24-hour blood pressure variability: An individual participant meta-analysis.
Siervo M, Lara J, Jajja A, Sutyarjoko A, Ashor AW, Brandt K, Qadir O, Mathers JC, Benjamin N, Winyard PG, Anning C, Shore A, Gilchrist M. Siervo M, et al. Among authors: shore a. Nitric Oxide. 2015 May 1;47:97-105. doi: 10.1016/j.niox.2015.04.007. Epub 2015 Apr 29. Nitric Oxide. 2015. PMID: 25937622
Two trials had an open-label, parallel design and two trials had a cross-over, double-blind design. Participants were randomised to either beetroot juice or placebo. ...Beetroot juice ingestion determined a significant decrease in nocturnal systolic BP variability i …
Two trials had an open-label, parallel design and two trials had a cross-over, double-blind design. Participants were randomised to e …
PP032. Unique features of long-term cardiovascular phenotype in young women with early-onset pre-eclampsia.
Lazdam M, de la Horra A, Diesch J, Francis J, Kenworthy Y, Shore A, Neubauer S, Kharbanda R, Alp N, Redman C, Kelly B, Leeson P. Lazdam M, et al. Among authors: shore a. Pregnancy Hypertens. 2012 Jul;2(3):259-60. doi: 10.1016/j.preghy.2012.04.143. Epub 2012 Jun 13. Pregnancy Hypertens. 2012. PMID: 26105355
INTRODUCTION: Early-onset preeclampsia is associated with a greater risk of cardiovascular disease than late-onset preeclampsia. ...RESULTS: All women with a previous history of preeclampsia had 5-10mmHg higher peripheral and central BP (P<0.001) as well as eleva …
INTRODUCTION: Early-onset preeclampsia is associated with a greater risk of cardiovascular disease than late-onset preeclampsia. ...R …
Measurement of Wall Shear Stress Exerted by Flowing Blood in the Human Carotid Artery: Ultrasound Doppler Velocimetry and Echo Particle Image Velocimetry.
Gates PE, Gurung A, Mazzaro L, Aizawa K, Elyas S, Strain WD, Shore AC, Shandas R. Gates PE, et al. Among authors: shore ac. Ultrasound Med Biol. 2018 Jul;44(7):1392-1401. doi: 10.1016/j.ultrasmedbio.2018.02.013. Epub 2018 Apr 17. Ultrasound Med Biol. 2018. PMID: 29678322 Free PMC article.
We have previously validated the use of a novel, ultrasound-based, particle image velocimetry technique (echo PIV) to compute 2-D velocity vector fields, which can easily be converted into WSS data. ...
We have previously validated the use of a novel, ultrasound-based, particle image velocimetry technique (echo PIV) to compute 2-D vel …
Echogenicity of the Common Carotid Artery Intima-Media Complex in Stroke.
Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Shore AC, Strain WD, Gates PE. Aizawa K, et al. Among authors: shore ac. Ultrasound Med Biol. 2016 May;42(5):1130-7. doi: 10.1016/j.ultrasmedbio.2016.01.006. Epub 2016 Mar 2. Ultrasound Med Biol. 2016. PMID: 26944528
The grey-scale median of the common carotid artery intima-media complex (IM-GSM) characterizes arterial wall composition, and a low IM-GSM is associated with increased cardiovascular mortality in the elderly. We aimed to determine differences in the IM-GSM between a
The grey-scale median of the common carotid artery intima-media complex (IM-GSM) characterizes arterial wall composition, and a low I …
Locally delivered GLP-1 analogues liraglutide and exenatide enhance microvascular perfusion in individuals with and without type 2 diabetes.
Aung MM, Slade K, Freeman LAR, Kos K, Whatmore JL, Shore AC, Gooding KM. Aung MM, et al. Among authors: shore ac. Diabetologia. 2019 Sep;62(9):1701-1711. doi: 10.1007/s00125-019-4918-x. Epub 2019 Jun 16. Diabetologia. 2019. PMID: 31203378 Free PMC article. Clinical Trial.
Liraglutide (0.06 mg), exenatide (0.5 μg) and saline (154 mmol/l NaCl; 0.9%) control were microinjected into separate sites in the dermis (forearm) in a randomised order, blinded to operator and participant. ...Study 2 participants, intervention and methods: in healthy ind …
Liraglutide (0.06 mg), exenatide (0.5 μg) and saline (154 mmol/l NaCl; 0.9%) control were microinjected into separate sites in the dermis (f …
Effects of dietary nitrate supplementation on the oxygen cost of exercise and walking performance in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled crossover trial.
Shepherd AI, Gilchrist M, Winyard PG, Jones AM, Hallmann E, Kazimierczak R, Rembialkowska E, Benjamin N, Shore AC, Wilkerson DP. Shepherd AI, et al. Among authors: shore ac. Free Radic Biol Med. 2015 Sep;86:200-8. doi: 10.1016/j.freeradbiomed.2015.05.014. Epub 2015 May 18. Free Radic Biol Med. 2015. PMID: 25998421 Clinical Trial.
In a randomized, double-blind, placebo-controlled crossover study, 48 participants with T2DM supplemented their diet for 4 days with either nitrate-rich beetroot juice (70ml/day, 6.43mmol nitrate/day) or nitrate-depleted beetroot juice as placebo (70ml/day, 0.07mmol nitrat …
In a randomized, double-blind, placebo-controlled crossover study, 48 participants with T2DM supplemented their diet for 4 days with …
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