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Oligonucleotide-directed gene-editing technology: mechanisms and future prospects.
Papaioannou I, Simons JP, Owen JS. Papaioannou I, et al. Expert Opin Biol Ther. 2012 Mar;12(3):329-42. doi: 10.1517/14712598.2012.660522. Epub 2012 Feb 10. Expert Opin Biol Ther. 2012. PMID: 22321001 Review.
INTRODUCTION: Gene editing, as defined here, uses short synthetic oligonucleotides to introduce small, site-specific changes into mammalian genomes, including repair of genetic point mutations. ...The final section focuses on the exciting tandem use of ssODNs with zinc …
INTRODUCTION: Gene editing, as defined here, uses short synthetic oligonucleotides to introduce small, site-specific changes into mam …
An autopsy case of Adams-Oliver syndrome.
Jun SY, Khang SK, Park SH. Jun SY, et al. J Korean Med Sci. 2000 Aug;15(4):482-4. doi: 10.3346/jkms.2000.15.4.482. J Korean Med Sci. 2000. PMID: 10983704 Free PMC article. Review.
On infantogram, all toe-bones were stubby and rudimentary. The middle and terminal phalanges of 2nd, 3rd & 5th fingers and the terminal phalange of 4th finger on the right hand were absent. The middle and terminal phalanges of 2nd & 5th fingers and terminal …
On infantogram, all toe-bones were stubby and rudimentary. The middle and terminal phalanges of 2nd, 3rd & 5th fingers and the te …
[Partial trisomy of the long arm of chromosome 6. A clinical case].
Dellacasa P, Bonanni P, Guerrini R. Dellacasa P, et al. Minerva Pediatr. 1993 Dec;45(12):517-21. Minerva Pediatr. 1993. PMID: 8145689 Review. Italian.
The phenotype is that characteristic of the syndrome: microbrachycephalia with a high and prominent forehead, "full" orbits, exophthalmos, antimongoloid palperbral fissures, hypertelorism, flattened root of the nose, antiverted nostrils, small mouth with thin lips, micrognathy, a …
The phenotype is that characteristic of the syndrome: microbrachycephalia with a high and prominent forehead, "full" orbits, exophthalmos, a …