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BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1.
Keutgens A, Zhang X, Shostak K, Robert I, Olivier S, Vanderplasschen A, Chapelle JP, Viatour P, Merville MP, Bex F, Gothot A, Chariot A. Keutgens A, et al. Among authors: shostak k. J Biol Chem. 2010 Aug 13;285(33):25831-40. doi: 10.1074/jbc.M110.112128. Epub 2010 Jun 17. J Biol Chem. 2010. PMID: 20558726 Free PMC article.
NF-κB-induced KIAA1199 promotes survival through EGFR signalling.
Shostak K, Zhang X, Hubert P, Göktuna SI, Jiang Z, Klevernic I, Hildebrand J, Roncarati P, Hennuy B, Ladang A, Somja J, Gothot A, Close P, Delvenne P, Chariot A. Shostak K, et al. Nat Commun. 2014 Nov 4;5:5232. doi: 10.1038/ncomms6232. Nat Commun. 2014. PMID: 25366117 Free PMC article.
A role for APPL1 in TLR3/4-dependent TBK1 and IKKε activation in macrophages.
Chau TL, Göktuna SI, Rammal A, Casanova T, Duong HQ, Gatot JS, Close P, Dejardin E, Desmecht D, Shostak K, Chariot A. Chau TL, et al. Among authors: shostak k. J Immunol. 2015 Apr 15;194(8):3970-83. doi: 10.4049/jimmunol.1401614. Epub 2015 Mar 16. J Immunol. 2015. PMID: 25780039
EGFR and NF-κB: partners in cancer.
Shostak K, Chariot A. Shostak K, et al. Trends Mol Med. 2015 Jun;21(6):385-93. doi: 10.1016/j.molmed.2015.04.001. Epub 2015 May 13. Trends Mol Med. 2015. PMID: 25979753 Review.
The Prosurvival IKK-Related Kinase IKKε Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine.
Göktuna SI, Shostak K, Chau TL, Heukamp LC, Hennuy B, Duong HQ, Ladang A, Close P, Klevernic I, Olivier F, Florin A, Ehx G, Baron F, Vandereyken M, Rahmouni S, Vereecke L, van Loo G, Büttner R, Greten FR, Chariot A. Göktuna SI, et al. Among authors: shostak k. Cancer Res. 2016 May 1;76(9):2587-99. doi: 10.1158/0008-5472.CAN-15-1473. Epub 2016 Mar 15. Cancer Res. 2016. PMID: 26980769 Free article.
Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer.
Delaunay S, Rapino F, Tharun L, Zhou Z, Heukamp L, Termathe M, Shostak K, Klevernic I, Florin A, Desmecht H, Desmet CJ, Nguyen L, Leidel SA, Willis AE, Büttner R, Chariot A, Close P. Delaunay S, et al. Among authors: shostak k. J Exp Med. 2016 Oct 17;213(11):2503-2523. doi: 10.1084/jem.20160397. Epub 2016 Oct 10. J Exp Med. 2016. PMID: 27811057 Free PMC article.
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