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Metabolic activation of the potent carcinogen dibenzo[a,h]anthracene by cDNA-expressed human cytochromes P450.
Shou M, Krausz KW, Gonzalez FJ, Gelboin HV. Shou M, et al. Arch Biochem Biophys. 1996 Apr 1;328(1):201-7. doi: 10.1006/abbi.1996.0161. Arch Biochem Biophys. 1996. PMID: 8638931
2,3-epoxy-4-hydroxynonanal, a potential lipid peroxidation product for etheno adduct formation, is not a substrate of human epoxide hydrolase.
Chen HJ, Gonzalez FJ, Shou M, Chung FL. Chen HJ, et al. Among authors: shou m. Carcinogenesis. 1998 May;19(5):939-43. doi: 10.1093/carcin/19.5.939. Carcinogenesis. 1998. PMID: 9635886
Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450.
Sai Y, Dai R, Yang TJ, Krausz KW, Gonzalez FJ, Gelboin HV, Shou M. Sai Y, et al. Among authors: shou m. Xenobiotica. 2000 Apr;30(4):327-43. doi: 10.1080/004982500237541. Xenobiotica. 2000. PMID: 10821163
Stereoselective epoxidation and hydration at the K-region of polycyclic aromatic hydrocarbons by cDNA-expressed cytochromes P450 1A1, 1A2, and epoxide hydrolase.
Shou M, Gonzalez FJ, Gelboin HV. Shou M, et al. Biochemistry. 1996 Dec 10;35(49):15807-13. doi: 10.1021/bi962042z. Biochemistry. 1996. PMID: 8961944
Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites.
Korzekwa KR, Krishnamachary N, Shou M, Ogai A, Parise RA, Rettie AE, Gonzalez FJ, Tracy TS. Korzekwa KR, et al. Among authors: shou m. Biochemistry. 1998 Mar 24;37(12):4137-47. doi: 10.1021/bi9715627. Biochemistry. 1998. PMID: 9521735
Stereospecific activation of the procarcinogen benzo[a]pyrene: a probe for the active sites of the cytochrome P450 superfamily.
Jones JP, Shou M, Korzekwa KR. Jones JP, et al. Among authors: shou m. Biochemistry. 1995 May 30;34(21):6956-61. doi: 10.1021/bi00021a007. Biochemistry. 1995. PMID: 7766605
The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol.
Shou M, Korzekwa KR, Crespi CL, Gonzalez FJ, Gelboin HV. Shou M, et al. Mol Carcinog. 1994 Jul;10(3):159-68. doi: 10.1002/mc.2940100307. Mol Carcinog. 1994. PMID: 8043197
3-Hydroxymethylcholanthrene: metabolic formation from 3-methylcholanthrene and stereoselective metabolism by rat liver microsomes.
Shou M, Yang SK. Shou M, et al. Drug Metab Dispos. 1996 May;24(5):595-601. Drug Metab Dispos. 1996. PMID: 8723742
9,10-Dihydroxy-9,10-dihydro-3-methylcholanthrene-2-one: a principal metabolite of the potent carcinogen 3-methylcholanthrene-2-one by rat liver microsomes.
Shou M, Yang SK. Shou M, et al. Carcinogenesis. 1990 Apr;11(4):689-95. doi: 10.1093/carcin/11.4.689. Carcinogenesis. 1990. PMID: 2323008
Monoclonal antibodies to cytochromes P450.
Gelboin HV, Shou M, Goldfarb I, Yang TJ, Krausz K. Gelboin HV, et al. Among authors: shou m. Methods Mol Biol. 1998;107:227-37. doi: 10.1385/0-89603-519-0:227. Methods Mol Biol. 1998. PMID: 14577233 No abstract available.
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