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Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics.
Kissinger CR, Rejto PA, Pelletier LA, Thomson JA, Showalter RE, Abreo MA, Agree CS, Margosiak S, Meng JJ, Aust RM, Vanderpool D, Li B, Tempczyk-Russell A, Villafranca JE. Kissinger CR, et al. J Mol Biol. 2004 Sep 17;342(3):943-52. doi: 10.1016/j.jmb.2004.07.071. J Mol Biol. 2004. PMID: 15342248
Cloning and nucleotide sequence of luxR, a regulatory gene controlling bioluminescence in Vibrio harveyi.
Showalter RE, Martin MO, Silverman MR. Showalter RE, et al. J Bacteriol. 1990 Jun;172(6):2946-54. doi: 10.1128/jb.172.6.2946-2954.1990. J Bacteriol. 1990. PMID: 2160932 Free PMC article.
Showalter, and M. Silverman, J. Bacteriol. 171:2406-2414, 1989). Mutants with transposon insertions in this regulatory locus were used to construct a hybridization probe which was used in this study to detect recombinants in a cosmid library containing the homologous DNA.
Showalter, and M. Silverman, J. Bacteriol. 171:2406-2414, 1989). Mutants with transposon insertions in this regulatory locus were use
Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis.
McTigue MA, Wickersham JA, Pinko C, Showalter RE, Parast CV, Tempczyk-Russell A, Gehring MR, Mroczkowski B, Kan CC, Villafranca JE, Appelt K. McTigue MA, et al. Structure. 1999 Mar 15;7(3):319-30. doi: 10.1016/s0969-2126(99)80042-2. Structure. 1999. PMID: 10368301
Genetic analysis in vibrio.
Silverman M, Showalter R, McCarter L. Silverman M, et al. Methods Enzymol. 1991;204:515-36. doi: 10.1016/0076-6879(91)04026-k. Methods Enzymol. 1991. PMID: 1943785 Review.
4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase.
Ellis DA, Blazel JK, Webber SE, Tran CV, Dragovich PS, Sun Z, Ruebsam F, McGuire HM, Xiang AX, Zhao J, Li LS, Zhou Y, Han Q, Kissinger CR, Showalter RE, Lardy M, Shah AM, Tsan M, Patel R, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. Ellis DA, et al. Among authors: showalter re. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4628-32. doi: 10.1016/j.bmcl.2008.07.014. Epub 2008 Jul 10. Bioorg Med Chem Lett. 2008. PMID: 18662878
Structure-based design of novel, urea-containing FKBP12 inhibitors.
Dragovich PS, Barker JE, French J, Imbacuan M, Kalish VJ, Kissinger CR, Knighton DR, Lewis CT, Moomaw EW, Parge HE, Pelletier LA, Prins TJ, Showalter RE, Tatlock JH, Tucker KD, Villafranca JE. Dragovich PS, et al. J Med Chem. 1996 Apr 26;39(9):1872-84. doi: 10.1021/jm950798a. J Med Chem. 1996. PMID: 8627611
5,6-Dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
Ruebsam F, Tran CV, Li LS, Kim SH, Xiang AX, Zhou Y, Blazel JK, Sun Z, Dragovich PS, Zhao J, McGuire HM, Murphy DE, Tran MT, Stankovic N, Ellis DA, Gobbi A, Showalter RE, Webber SE, Shah AM, Tsan M, Patel RA, Lebrun LA, Hou HJ, Kamran R, Sergeeva MV, Bartkowski DM, Nolan TG, Norris DA, Kirkovsky L. Ruebsam F, et al. Among authors: showalter re. Bioorg Med Chem Lett. 2009 Jan 15;19(2):451-8. doi: 10.1016/j.bmcl.2008.11.048. Epub 2008 Nov 18. Bioorg Med Chem Lett. 2009. PMID: 19054673
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