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Targeting the PIAS1 SUMO ligase pathway to control inflammation.
Liu B, Shuai K. Liu B, et al. Trends Pharmacol Sci. 2008 Oct;29(10):505-9. doi: 10.1016/j.tips.2008.07.008. Epub 2008 Aug 26. Trends Pharmacol Sci. 2008. PMID: 18755518 Free PMC article.
Control of specificity and magnitude of NF-kappa B and STAT1-mediated gene activation through PIASy and PIAS1 cooperation.
Tahk S, Liu B, Chernishof V, Wong KA, Wu H, Shuai K. Tahk S, et al. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11643-8. doi: 10.1073/pnas.0701877104. Epub 2007 Jul 2. Proc Natl Acad Sci U S A. 2007. PMID: 17606919 Free PMC article.
Regulation of cytokine signaling pathways by PIAS proteins.
Shuai K. Shuai K. Cell Res. 2006 Feb;16(2):196-202. doi: 10.1038/sj.cr.7310027. Cell Res. 2006. PMID: 16474434 Review.
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling.
Fan G, Martinowich K, Chin MH, He F, Fouse SD, Hutnick L, Hattori D, Ge W, Shen Y, Wu H, ten Hoeve J, Shuai K, Sun YE. Fan G, et al. Development. 2005 Aug;132(15):3345-56. doi: 10.1242/dev.01912. Development. 2005. PMID: 16014513
Negative regulation of NF-kappaB signaling by PIAS1.
Liu B, Yang R, Wong KA, Getman C, Stein N, Teitell MA, Cheng G, Wu H, Shuai K. Liu B, et al. Mol Cell Biol. 2005 Feb;25(3):1113-23. doi: 10.1128/MCB.25.3.1113-1123.2005. Mol Cell Biol. 2005. PMID: 15657437 Free PMC article.
Serine phosphorylation: arming Stat1 against infection.
Shuai K. Shuai K. Immunity. 2003 Dec;19(6):771-2. doi: 10.1016/s1074-7613(03)00329-7. Immunity. 2003. PMID: 14670293
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