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H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction.
Healton SE, Pinto HD, Mishra LN, Hamilton GA, Wheat JC, Swist-Rosowska K, Shukeir N, Dou Y, Steidl U, Jenuwein T, Gamble MJ, Skoultchi AI. Healton SE, et al. Among authors: shukeir n. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14251-14258. doi: 10.1073/pnas.1920725117. Epub 2020 Jun 8. Proc Natl Acad Sci U S A. 2020. PMID: 32513732 Free PMC article.
Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation.
Velazquez Camacho O, Galan C, Swist-Rosowska K, Ching R, Gamalinda M, Karabiber F, De La Rosa-Velazquez I, Engist B, Koschorz B, Shukeir N, Onishi-Seebacher M, van de Nobelen S, Jenuwein T. Velazquez Camacho O, et al. Among authors: shukeir n. Elife. 2017 Aug 1;6:e25293. doi: 10.7554/eLife.25293. Elife. 2017. PMID: 28760199 Free PMC article.
A transcription factor-based mechanism for mouse heterochromatin formation.
Bulut-Karslioglu A, Perrera V, Scaranaro M, de la Rosa-Velazquez IA, van de Nobelen S, Shukeir N, Popow J, Gerle B, Opravil S, Pagani M, Meidhof S, Brabletz T, Manke T, Lachner M, Jenuwein T. Bulut-Karslioglu A, et al. Among authors: shukeir n. Nat Struct Mol Biol. 2012 Oct;19(10):1023-30. doi: 10.1038/nsmb.2382. Epub 2012 Sep 16. Nat Struct Mol Biol. 2012. PMID: 22983563
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