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GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.
Thomsen ARB, Plouffe B, Cahill TJ 3rd, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ. Thomsen ARB, et al. Among authors: shukla ak. Cell. 2016 Aug 11;166(4):907-919. doi: 10.1016/j.cell.2016.07.004. Epub 2016 Aug 4. Cell. 2016. PMID: 27499021 Free PMC article.
A crystal clear view of the beta2-adrenergic receptor.
Lefkowitz RJ, Sun JP, Shukla AK. Lefkowitz RJ, et al. Among authors: shukla ak. Nat Biotechnol. 2008 Feb;26(2):189-91. doi: 10.1038/nbt0208-189. Nat Biotechnol. 2008. PMID: 18259173 No abstract available.
Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2.
Shenoy SK, Modi AS, Shukla AK, Xiao K, Berthouze M, Ahn S, Wilkinson KD, Miller WE, Lefkowitz RJ. Shenoy SK, et al. Among authors: shukla ak. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6650-5. doi: 10.1073/pnas.0901083106. Epub 2009 Apr 10. Proc Natl Acad Sci U S A. 2009. PMID: 19363159 Free PMC article.
524 results