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STAT3 inhibition of gluconeogenesis is downregulated by SirT1.
Nie Y, Erion DM, Yuan Z, Dietrich M, Shulman GI, Horvath TL, Gao Q. Nie Y, et al. Among authors: shulman gi. Nat Cell Biol. 2009 Apr;11(4):492-500. doi: 10.1038/ncb1857. Epub 2009 Mar 22. Nat Cell Biol. 2009. PMID: 19295512 Free PMC article.
SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats.
Erion DM, Yonemitsu S, Nie Y, Nagai Y, Gillum MP, Hsiao JJ, Iwasaki T, Stark R, Weismann D, Yu XX, Murray SF, Bhanot S, Monia BP, Horvath TL, Gao Q, Samuel VT, Shulman GI. Erion DM, et al. Among authors: shulman gi. Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11288-93. doi: 10.1073/pnas.0812931106. Epub 2009 Jun 22. Proc Natl Acad Sci U S A. 2009. PMID: 19549853 Free PMC article.
Sirtuin-1 regulation of mammalian metabolism.
Gillum MP, Erion DM, Shulman GI. Gillum MP, et al. Among authors: shulman gi. Trends Mol Med. 2011 Jan;17(1):8-13. doi: 10.1016/j.molmed.2010.09.005. Trends Mol Med. 2011. PMID: 20971038 Free PMC article. Review.
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, Kibbey RG, Shulman GI. Madiraju AK, et al. Among authors: shulman gi. Nature. 2014 Jun 26;510(7506):542-6. doi: 10.1038/nature13270. Epub 2014 May 21. Nature. 2014. PMID: 24847880 Free PMC article.
UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals.
Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschöp MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S. Andrews ZB, et al. Among authors: shulman gi. Nature. 2008 Aug 14;454(7206):846-51. doi: 10.1038/nature07181. Epub 2008 Jul 30. Nature. 2008. PMID: 18668043 Free PMC article.
Diacylglycerol-mediated insulin resistance.
Erion DM, Shulman GI. Erion DM, et al. Among authors: shulman gi. Nat Med. 2010 Apr;16(4):400-2. doi: 10.1038/nm0410-400. Nat Med. 2010. PMID: 20376053 Free PMC article.
SirT1 regulates adipose tissue inflammation.
Gillum MP, Kotas ME, Erion DM, Kursawe R, Chatterjee P, Nead KT, Muise ES, Hsiao JJ, Frederick DW, Yonemitsu S, Banks AS, Qiang L, Bhanot S, Olefsky JM, Sears DD, Caprio S, Shulman GI. Gillum MP, et al. Among authors: shulman gi. Diabetes. 2011 Dec;60(12):3235-45. doi: 10.2337/db11-0616. Diabetes. 2011. PMID: 22110092 Free PMC article.
590 results