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Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling.
Skardal A, Shupe T, Atala A. Skardal A, et al. Among authors: shupe t. Drug Discov Today. 2016 Sep;21(9):1399-1411. doi: 10.1016/j.drudis.2016.07.003. Epub 2016 Jul 12. Drug Discov Today. 2016. PMID: 27422270 Review.
Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform.
Skardal A, Murphy SV, Devarasetty M, Mead I, Kang HW, Seol YJ, Shrike Zhang Y, Shin SR, Zhao L, Aleman J, Hall AR, Shupe TD, Kleensang A, Dokmeci MR, Jin Lee S, Jackson JD, Yoo JJ, Hartung T, Khademhosseini A, Soker S, Bishop CE, Atala A. Skardal A, et al. Among authors: shupe td. Sci Rep. 2017 Aug 18;7(1):8837. doi: 10.1038/s41598-017-08879-x. Sci Rep. 2017. PMID: 28821762 Free PMC article.
Optical Tracking and Digital Quantification of Beating Behavior in Bioengineered Human Cardiac Organoids.
Devarasetty M, Forsythe S, Shupe TD, Soker S, Bishop CE, Atala A, Skardal A. Devarasetty M, et al. Among authors: shupe td. Biosensors (Basel). 2017 Jun 23;7(3):24. doi: 10.3390/bios7030024. Biosensors (Basel). 2017. PMID: 28644395 Free PMC article.
Stiffness of hyaluronic acid gels containing liver extracellular matrix supports human hepatocyte function and alters cell morphology.
Deegan DB, Zimmerman C, Skardal A, Atala A, Shupe TD. Deegan DB, et al. J Mech Behav Biomed Mater. 2015 Mar;55:87-103. doi: 10.1016/j.jmbbm.2015.10.016. Epub 2015 Oct 30. J Mech Behav Biomed Mater. 2015. PMID: 26569044
Immunogenicity of decellularized porcine liver for bioengineered hepatic tissue.
Mirmalek-Sani SH, Sullivan DC, Zimmerman C, Shupe TD, Petersen BE. Mirmalek-Sani SH, et al. Am J Pathol. 2013 Aug;183(2):558-65. doi: 10.1016/j.ajpath.2013.05.002. Epub 2013 Jun 7. Am J Pathol. 2013. PMID: 23747949 Free PMC article.
A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs.
Skardal A, Devarasetty M, Kang HW, Mead I, Bishop C, Shupe T, Lee SJ, Jackson J, Yoo J, Soker S, Atala A. Skardal A, et al. Among authors: shupe t. Acta Biomater. 2015 Oct;25:24-34. doi: 10.1016/j.actbio.2015.07.030. Epub 2015 Jul 22. Acta Biomater. 2015. PMID: 26210285
Environmental Toxin Screening Using Human-Derived 3D Bioengineered Liver and Cardiac Organoids.
Forsythe SD, Devarasetty M, Shupe T, Bishop C, Atala A, Soker S, Skardal A. Forsythe SD, et al. Among authors: shupe t. Front Public Health. 2018 Apr 16;6:103. doi: 10.3389/fpubh.2018.00103. eCollection 2018. Front Public Health. 2018. PMID: 29755963 Free PMC article.
Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors.
Zhang YS, Aleman J, Shin SR, Kilic T, Kim D, Mousavi Shaegh SA, Massa S, Riahi R, Chae S, Hu N, Avci H, Zhang W, Silvestri A, Sanati Nezhad A, Manbohi A, De Ferrari F, Polini A, Calzone G, Shaikh N, Alerasool P, Budina E, Kang J, Bhise N, Ribas J, Pourmand A, Skardal A, Shupe T, Bishop CE, Dokmeci MR, Atala A, Khademhosseini A. Zhang YS, et al. Among authors: shupe t. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2293-E2302. doi: 10.1073/pnas.1612906114. Epub 2017 Mar 6. Proc Natl Acad Sci U S A. 2017. PMID: 28265064 Free PMC article.
Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip.
Zhang YS, Arneri A, Bersini S, Shin SR, Zhu K, Goli-Malekabadi Z, Aleman J, Colosi C, Busignani F, Dell'Erba V, Bishop C, Shupe T, Demarchi D, Moretti M, Rasponi M, Dokmeci MR, Atala A, Khademhosseini A. Zhang YS, et al. Among authors: shupe t. Biomaterials. 2016 Dec;110:45-59. doi: 10.1016/j.biomaterials.2016.09.003. Epub 2016 Sep 5. Biomaterials. 2016. PMID: 27710832 Free PMC article.
Cell and organ bioengineering technology as applied to gastrointestinal diseases.
Orlando G, Domínguez-Bendala J, Shupe T, Bergman C, Bitar KN, Booth C, Carbone M, Koch KL, Lerut JP, Neuberger JM, Petersen B, Ricordi C, Atala A, Stratta RJ, Soker S. Orlando G, et al. Among authors: shupe t. Gut. 2013 May;62(5):774-86. doi: 10.1136/gutjnl-2011-301111. Epub 2012 Jan 20. Gut. 2013. PMID: 22267591 Review.
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