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The Lin28/let-7 axis regulates glucose metabolism.
Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI; DIAGRAM Consortium; MAGIC Investigators; Altshuler D, Daley GQ. Zhu H, et al. Cell. 2011 Sep 30;147(1):81-94. doi: 10.1016/j.cell.2011.08.033. Cell. 2011. PMID: 21962509 Free PMC article.
Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis.
Zhang WC, Shyh-Chang N, Yang H, Rai A, Umashankar S, Ma S, Soh BS, Sun LL, Tai BC, Nga ME, Bhakoo KK, Jayapal SR, Nichane M, Yu Q, Ahmed DA, Tan C, Sing WP, Tam J, Thirugananam A, Noghabi MS, Pang YH, Ang HS, Mitchell W, Robson P, Kaldis P, Soo RA, Swarup S, Lim EH, Lim B. Zhang WC, et al. Cell. 2012 Jan 20;148(1-2):259-72. doi: 10.1016/j.cell.2011.11.050. Epub 2012 Jan 5. Cell. 2012. PMID: 22225612 Free article.
Influence of threonine metabolism on S-adenosylmethionine and histone methylation.
Shyh-Chang N, Locasale JW, Lyssiotis CA, Zheng Y, Teo RY, Ratanasirintrawoot S, Zhang J, Onder T, Unternaehrer JJ, Zhu H, Asara JM, Daley GQ, Cantley LC. Shyh-Chang N, et al. Science. 2013 Jan 11;339(6116):222-6. doi: 10.1126/science.1226603. Epub 2012 Nov 1. Science. 2013. PMID: 23118012 Free PMC article.
Stem cell metabolism in tissue development and aging.
Shyh-Chang N, Daley GQ, Cantley LC. Shyh-Chang N, et al. Development. 2013 Jun;140(12):2535-47. doi: 10.1242/dev.091777. Development. 2013. PMID: 23715547 Free PMC article. Review.
Lin28 enhances tissue repair by reprogramming cellular metabolism.
Shyh-Chang N, Zhu H, Yvanka de Soysa T, Shinoda G, Seligson MT, Tsanov KM, Nguyen L, Asara JM, Cantley LC, Daley GQ. Shyh-Chang N, et al. Cell. 2013 Nov 7;155(4):778-92. doi: 10.1016/j.cell.2013.09.059. Cell. 2013. PMID: 24209617 Free PMC article.
Precise let-7 expression levels balance organ regeneration against tumor suppression.
Wu L, Nguyen LH, Zhou K, de Soysa TY, Li L, Miller JB, Tian J, Locker J, Zhang S, Shinoda G, Seligson MT, Zeitels LR, Acharya A, Wang SC, Mendell JT, He X, Nishino J, Morrison SJ, Siegwart DJ, Daley GQ, Shyh-Chang N, Zhu H. Wu L, et al. Elife. 2015 Oct 7;4:e09431. doi: 10.7554/eLife.09431. Elife. 2015. PMID: 26445246 Free PMC article.
57 results