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Molecular biology of dopamine receptors.

Sibley DR, Monsma FJ Jr. Sibley DR, et al. Trends Pharmacol Sci. 1992 Feb;13(2):61-9. doi: 10.1016/0165-6147(92)90025-2. Trends Pharmacol Sci. 1992. PMID: 1561715 Review.

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Pharmacological characterization of mammalian D1 and D2 dopamine receptors expressed in Drosophila Schneider-2 cells.

Schetz JA, Kim OJ, Sibley DR. Schetz JA, et al. Among authors: sibley dr. J Recept Signal Transduct Res. 2003 Feb;23(1):99-109. doi: 10.1081/rrs-120018763. J Recept Signal Transduct Res. 2003. PMID: 12680592 Free PMC article.

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D1-like dopamine receptor-mediated function in congenic mutants with D1 vs. D5 receptor "knockout".

O'Sullivan GJ, Clifford JJ, Tomiyama K, Koshikawa N, Drago J, Sibley DR, Croke DT, Waddington JL. O'Sullivan GJ, et al. Among authors: sibley dr. J Recept Signal Transduct Res. 2004 Aug;24(3):107-16. doi: 10.1081/rrs-200032078. J Recept Signal Transduct Res. 2004. PMID: 15521357

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New roles for dopamine D₂ and D₃ receptors in pancreatic beta cell insulin secretion.

Farino ZJ, Morgenstern TJ, Maffei A, Quick M, De Solis AJ, Wiriyasermkul P, Freyberg RJ, Aslanoglou D, Sorisio D, Inbar BP, Free RB, Donthamsetti P, Mosharov EV, Kellendonk C, Schwartz GJ, Sibley DR, Schmauss C, Zeltser LM, Moore H, Harris PE, Javitch JA, Freyberg Z. Farino ZJ, et al. Among authors: sibley dr. Mol Psychiatry. 2020 Sep;25(9):2070-2085. doi: 10.1038/s41380-018-0344-6. Epub 2019 Jan 9. Mol Psychiatry. 2020. PMID: 30626912 Free PMC article.

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Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D₂ Dopamine Receptor.

Chun LS, Vekariya RH, Free RB, Li Y, Lin DT, Su P, Liu F, Namkung Y, Laporte SA, Moritz AE, Aubé J, Frankowski KJ, Sibley DR. Chun LS, et al. Among authors: sibley dr. Front Synaptic Neurosci. 2018 Feb 21;10:2. doi: 10.3389/fnsyn.2018.00002. eCollection 2018. Front Synaptic Neurosci. 2018. PMID: 29515433 Free PMC article.

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The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors.

Verma RK, Abramyan AM, Michino M, Free RB, Sibley DR, Javitch JA, Lane JR, Shi L. Verma RK, et al. Among authors: sibley dr. PLoS Comput Biol. 2018 Jan 16;14(1):e1005948. doi: 10.1371/journal.pcbi.1005948. eCollection 2018 Jan. PLoS Comput Biol. 2018. PMID: 29337986 Free PMC article.

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Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D₃ Receptor (D₃R).

Kumar V, Moritz AE, Keck TM, Bonifazi A, Ellenberger MP, Sibley CD, Free RB, Shi L, Lane JR, Sibley DR, Newman AH. Kumar V, et al. Among authors: sibley cd, sibley dr. J Med Chem. 2017 Feb 23;60(4):1478-1494. doi: 10.1021/acs.jmedchem.6b01688. Epub 2017 Feb 10. J Med Chem. 2017. PMID: 28186762 Free PMC article.

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Medication discovery for addiction: translating the dopamine D3 receptor hypothesis.

Newman AH, Blaylock BL, Nader MA, Bergman J, Sibley DR, Skolnick P. Newman AH, et al. Among authors: sibley dr. Biochem Pharmacol. 2012 Oct 1;84(7):882-90. doi: 10.1016/j.bcp.2012.06.023. Epub 2012 Jul 3. Biochem Pharmacol. 2012. PMID: 22781742 Free PMC article. Review.

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Dopamine beta-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding.

Skinbjerg M, Seneca N, Liow JS, Hong J, Weinshenker D, Pike VW, Halldin C, Sibley DR, Innis RB. Skinbjerg M, et al. Among authors: sibley dr. Synapse. 2010 Sep;64(9):699-703. doi: 10.1002/syn.20781. Synapse. 2010. PMID: 20336622 Free PMC article.

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Kinetic brain analysis and whole-body imaging in monkey of [11C]MNPA: a dopamine agonist radioligand.

Seneca N, Skinbjerg M, Zoghbi SS, Liow JS, Gladding RL, Hong J, Kannan P, Tuan E, Sibley DR, Halldin C, Pike VW, Innis RB. Seneca N, et al. Among authors: sibley dr. Synapse. 2008 Sep;62(9):700-9. doi: 10.1002/syn.20544. Synapse. 2008. PMID: 18566975 Free PMC article.

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