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Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model.
van Giezen JJ, Sidaway J, Glaves P, Kirk I, Björkman JA. van Giezen JJ, et al. Among authors: sidaway j. J Cardiovasc Pharmacol Ther. 2012 Jun;17(2):164-72. doi: 10.1177/1074248411410883. Epub 2011 Jun 22. J Cardiovasc Pharmacol Ther. 2012. PMID: 21697355
Characterization of the adenosine pharmacology of ticagrelor reveals therapeutically relevant inhibition of equilibrative nucleoside transporter 1.
Armstrong D, Summers C, Ewart L, Nylander S, Sidaway JE, van Giezen JJ. Armstrong D, et al. Among authors: sidaway je. J Cardiovasc Pharmacol Ther. 2014 Mar;19(2):209-19. doi: 10.1177/1074248413511693. Epub 2014 Jan 10. J Cardiovasc Pharmacol Ther. 2014. PMID: 24414167
Towards better models and mechanistic biomarkers for drug-induced gastrointestinal injury.
Carr DF, Ayehunie S, Davies A, Duckworth CA, French S, Hall N, Hussain S, Mellor HR, Norris A, Park BK, Penrose A, Pritchard DM, Probert CS, Ramaiah S, Sadler C, Schmitt M, Shaw A, Sidaway JE, Vries RG, Wagoner M, Pirmohamed M. Carr DF, et al. Among authors: sidaway je. Pharmacol Ther. 2017 Apr;172:181-194. doi: 10.1016/j.pharmthera.2017.01.002. Epub 2017 Jan 27. Pharmacol Ther. 2017. PMID: 28132905 Review.
MicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity.
Kia R, Kelly L, Sison-Young RL, Zhang F, Pridgeon CS, Heslop JA, Metcalfe P, Kitteringham NR, Baxter M, Harrison S, Hanley NA, Burke ZD, Storm MP, Welham MJ, Tosh D, Küppers-Munther B, Edsbagge J, Starkey Lewis PJ, Bonner F, Harpur E, Sidaway J, Bowes J, Fenwick SW, Malik H, Goldring CE, Park BK. Kia R, et al. Among authors: sidaway j. Toxicol Sci. 2015 Mar;144(1):173-85. doi: 10.1093/toxsci/kfu269. Epub 2014 Dec 18. Toxicol Sci. 2015. PMID: 25527335 Free PMC article.
Preclinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies.
Scarfe L, Brillant N, Kumar JD, Ali N, Alrumayh A, Amali M, Barbellion S, Jones V, Niemeijer M, Potdevin S, Roussignol G, Vaganov A, Barbaric I, Barrow M, Burton NC, Connell J, Dazzi F, Edsbagge J, French NS, Holder J, Hutchinson C, Jones DR, Kalber T, Lovatt C, Lythgoe MF, Patel S, Patrick PS, Piner J, Reinhardt J, Ricci E, Sidaway J, Stacey GN, Starkey Lewis PJ, Sullivan G, Taylor A, Wilm B, Poptani H, Murray P, Goldring CEP, Park BK. Scarfe L, et al. Among authors: sidaway j. NPJ Regen Med. 2017 Oct 19;2:28. doi: 10.1038/s41536-017-0029-9. eCollection 2017. NPJ Regen Med. 2017. PMID: 29302362 Free PMC article. Review.
Safety pharmacology--current and emerging concepts.
Hamdam J, Sethu S, Smith T, Alfirevic A, Alhaidari M, Atkinson J, Ayala M, Box H, Cross M, Delaunois A, Dermody A, Govindappa K, Guillon JM, Jenkins R, Kenna G, Lemmer B, Meecham K, Olayanju A, Pestel S, Rothfuss A, Sidaway J, Sison-Young R, Smith E, Stebbings R, Tingle Y, Valentin JP, Williams A, Williams D, Park K, Goldring C. Hamdam J, et al. Among authors: sidaway j. Toxicol Appl Pharmacol. 2013 Dec 1;273(2):229-41. doi: 10.1016/j.taap.2013.04.039. Epub 2013 Jun 1. Toxicol Appl Pharmacol. 2013. PMID: 23732082 Review.
Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms.
Pridgeon CS, Schlott C, Wong MW, Heringa MB, Heckel T, Leedale J, Launay L, Gryshkova V, Przyborski S, Bearon RN, Wilkinson EL, Ansari T, Greenman J, Hendriks DFG, Gibbs S, Sidaway J, Sison-Young RL, Walker P, Cross MJ, Park BK, Goldring CEP. Pridgeon CS, et al. Among authors: sidaway j. Arch Toxicol. 2018 Feb;92(2):557-569. doi: 10.1007/s00204-018-2152-9. Epub 2018 Jan 23. Arch Toxicol. 2018. PMID: 29362863 Free PMC article. Review.
Phenobarbitone-induced liver response in wild type and in p53 deficient mice.
Gould S, Sidaway J, Sansom N, Betton G, Orton T. Gould S, et al. Among authors: sidaway j. Toxicol Lett. 2001 Jun 20;122(2):131-40. doi: 10.1016/s0378-4274(01)00349-6. Toxicol Lett. 2001. PMID: 11439219
Identification of phenobarbitone-modulated genes in mouse liver by differential display.
Garcia-Allan C, Lord PG, Loughlin JM, Orton TC, Sidaway JE. Garcia-Allan C, et al. Among authors: sidaway je. J Biochem Mol Toxicol. 2000;14(2):65-72. doi: 10.1002/(sici)1099-0461(2000)14:2<65::aid-jbt1>3.0.co;2-#. J Biochem Mol Toxicol. 2000. PMID: 10630419
Physiological, pharmacological and toxicological considerations of drug-induced structural cardiac injury.
Cross MJ, Berridge BR, Clements PJ, Cove-Smith L, Force TL, Hoffmann P, Holbrook M, Lyon AR, Mellor HR, Norris AA, Pirmohamed M, Tugwood JD, Sidaway JE, Park BK. Cross MJ, et al. Among authors: sidaway je. Br J Pharmacol. 2015 Feb;172(4):957-74. doi: 10.1111/bph.12979. Epub 2015 Jan 12. Br J Pharmacol. 2015. PMID: 25302413 Free PMC article. Review.
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