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Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic.
Mendez AS, Alfaro J, Morales-Soto MA, Dar AC, McCullagh E, Gotthardt K, Li H, Acosta-Alvear D, Sidrauski C, Korennykh AV, Bernales S, Shokat KM, Walter P. Mendez AS, et al. Among authors: sidrauski c. Elife. 2015 May 19;4:e05434. doi: 10.7554/eLife.05434. Elife. 2015. PMID: 25986605 Free PMC article.
Pharmacological brake-release of mRNA translation enhances cognitive memory.
Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin MR, Renslo AR, Sonenberg N, Walter P. Sidrauski C, et al. Elife. 2013 May 28;2:e00498. doi: 10.7554/eLife.00498. Elife. 2013. PMID: 23741617 Free PMC article.
Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway.
Gonzalez TN, Sidrauski C, Dörfler S, Walter P. Gonzalez TN, et al. EMBO J. 1999 Jun 1;18(11):3119-32. doi: 10.1093/emboj/18.11.3119. EMBO J. 1999. PMID: 10357823 Free PMC article.
Intracellular signaling from the endoplasmic reticulum to the nucleus.
Chapman R, Sidrauski C, Walter P. Chapman R, et al. Annu Rev Cell Dev Biol. 1998;14:459-85. doi: 10.1146/annurev.cellbio.14.1.459. Annu Rev Cell Dev Biol. 1998. PMID: 9891790 Review.
Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response.
Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P. Sidrauski C, et al. Elife. 2015 Apr 15;4:e07314. doi: 10.7554/eLife.07314. Elife. 2015. PMID: 25875391 Free PMC article.
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